Journal List > J Korean Diabetes > v.12(1) > 1054814

Jang, Kim, Lee, Song, and Kim: A Case of Type 2 Diabetes Mellitus Improved after Surgical Treatment of Primary Hyperparathyroidism

Abstract

Patients with primary hyperparathyroidism often exhibit insulin resistance and glucose intolerance. In previous studies, glucose intolerance was improved by parathyroidectomy in primary hyperparathyroidism. We report a case of type 2 diabetes mellitus that improved after resection of a parathyroid adenoma along with a review of the literature.

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Fig. 1.
(A) 99mTc-setamibi scan showed nodular hot uptake in the left lower neck in early image (15 min). (B) In a delayed image (2 hr 30 min), accumulation of abnormal radioactivity in the left lower neck remained after washout of the thyroid gland activity.
jkd-12-60f1.tif
Fig. 2.
(A) Gross specimen of parathyroid adenoma (4.7 × 3.1 × 1.5 cm). (B) Microscopically (H&E, ×200), the adenoma is partly encapsulated and shows a solid sheet of tumor cells with mainly clear cytoplasm and round nuclei. Nuclear atypia is minimal and the mitotic activity is very low.
jkd-12-60f2.tif
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