A Case of Type 2 Diabetes Mellitus Improved after Surgical Treatment of Primary Hyperparathyroidism

Yun-Mi Jang; Dong Lim Kim; Eun Jung Lee; Kee-Ho Song; Suk Kyeong Kim

doi:10.4093/jkd.2011.12.1.60

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Jang, Kim, Lee, Song, and Kim: A Case of Type 2 Diabetes Mellitus Improved after Surgical Treatment of Primary Hyperparathyroidism

Original Articles & Case Reports

J Korean Diabetes 2011;12(1):60-63.

Published online: 22 January 2011

DOI: https://doi.org/10.4093/jkd.2011.12.1.60

A Case of Type 2 Diabetes Mellitus Improved after Surgical Treatment of Primary Hyperparathyroidism

Yun-Mi Jang, Dong Lim Kim, Eun Jung Lee, Kee-Ho Song, Suk Kyeong Kim

Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Patients with primary hyperparathyroidism often exhibit insulin resistance and glucose intolerance. In previous studies, glucose intolerance was improved by parathyroidectomy in primary hyperparathyroidism. We report a case of type 2 diabetes mellitus that improved after resection of a parathyroid adenoma along with a review of the literature.

Keywords: Hyperparathyroidism, Diabetes, Glucose intolerance

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Fig. 1.

(A) ^99mTc-setamibi scan showed nodular hot uptake in the left lower neck in early image (15 min). (B) In a delayed image (2 hr 30 min), accumulation of abnormal radioactivity in the left lower neck remained after washout of the thyroid gland activity.

Fig. 2.

(A) Gross specimen of parathyroid adenoma (4.7 × 3.1 × 1.5 cm). (B) Microscopically (H&E, ×200), the adenoma is partly encapsulated and shows a solid sheet of tumor cells with mainly clear cytoplasm and round nuclei. Nuclear atypia is minimal and the mitotic activity is very low.

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