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Yoon, Kim, and Kim: Prediction of Neurological Recovery in Patients with Hypoxic-ischemic Encephalopathy
Review

Brain & Neurorehabilitation 2014; 7(1): 5-9.

Published online: 31 March 2014

DOI: https://doi.org/10.12786/bn.2014.7.1.5

Prediction of Neurological Recovery in Patients with Hypoxic-ischemic Encephalopathy

Seo Yeon Yoon, M.D., Je Kyung Kim, M.D., Yong Wook Kim, M.D., Ph.D.

Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Korea.

Correspondence to: Yong Wook Kim, Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul 120-752, Korea. Tel: 02-2228-7316, Fax: 02-363-2795, ywkim1@yuhs.ac

Copyright © 2014 Korean Society for Neurorehabilitation

Abstract

The incidence of hypoxic-ischemic encephalopathy (HIE) is not well known, however, the common causes of hypoxic-ischemic encephalopathy are sudden cardiac arrest, acute respiratory failure and carbon monoxide poisoning. Due to high metabolic demand, the brain is very susceptible to damage from deprivation of blood supply and oxygen delivery. When patients recover from comatose after HIE, there are various spectrums of neurological outcomes, ranging from vegetative state to good recovery. Various methods including neurologic examination, neurophysiologic and biochemical tools, neuroimaging technique have been proposed for the prognostic evaluation of HIE. This article reviews the pathophysiology of HIE and predictive methods for neurological recovery after HIE.

Keywords: hypoxic-ischemic encephalopathy, neurological recovery, prediction

Figures and Tables

Table 1
Classification of Hypoxic-Ischemic Encephalopathy
bn-7-5-i001

Notes

This work was supported by a faculty research grant of Yonsei University College of Medicine for 2010 (6-2010-0034), Seoul, Republic of Korea.

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