Journal List > J Korean Bone Joint Tumor Soc > v.17(2) > 1051999

Park, Jung, and Nah: Double Primary Presentation of Liposarcoma and Ewing's Sarcoma: A Case Report

Abstract

The development of different entities of soft tissue sarcoma in one patient is rare. It usually affects head and neck or abdominal region, whereas those affecting the extremities are much rarer. We describe a patient with double primary presentation of liposarcoma and Ewing's sarcoma in extremity. This case implies that sarcoma patients are at increased risk of a second malignancy, and this implies a need to search for occult tumors during follow up.

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Figure 1.
(A) Axial T2-weighted fat-saturated image, (B) Axial T1-weighted image, and (C) gadolinium enhancing image showing mass in proximal thigh.
jkbjts-17-95f1.tif
Figure 2.
Tc99-bone scans showing diffuse uptake left proximal thigh and no other site of disease. (A) Anteroposterior, and (B) posteroanterior bone scan view.
jkbjts-17-95f2.tif
Figure 3.
(A) A high-power photomicrograph of the specimen shows findings compatible with liposarcoma (Stain, hematoxylin & eosin; magnification, ×200) and (B) positive S-100 immunohistochemical analysis stain.
jkbjts-17-95f3.tif
Figure 4.
2 years and 6 months follow up radiographs showing a new osteolytic lesion in proximal tibia. Anteroposterior (A) and lateral view (B).
jkbjts-17-95f4.tif
Figure 5.
Magnetic resonance imaging showing heterogenous enhancing mass. (A) proximal tibia and (B) left ilium.
jkbjts-17-95f5.tif
Figure 6.
Pathology revealing ES/PNET. (A) photomicrograph (Stain, hematoxylin & eosin; magnification, ×200), (B) CD56, (C) CD99, and (D) FLI-1 of immunohistochemical analysis.
jkbjts-17-95f6.tif
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