Abstract
Purpose
Liquid-based cytology have been developed and currently used to overcome the limitation of conventional cytology. This study aims to evaluate the differences between conventional cytology and ThinPrep® in the bronchial washing.
Materials and Methods
Both conventional cytology and ThinPrep® were performed in the 2,551 cases of bronchial washing, of which, 116 cases of histologically diagnosed as lung cancer were evaluated.
Results
Among the 116 cases, 23 and 4 cases were negative in conventional cytology and ThinPrep®, respectively. The thirty eight cases in conventional cytology and 30 cases in ThinPrep® were diagnosed as "atypical." Malignant carcinoma was 54 cases and 82 cases in conventional cytology and ThinPrep®, respectively. The positive predictive value, negative predictive value, sensitivity and specificity were 98.94%, 99.06%, 80.17%, and 99.96%, respectively in conventional cytology. Those were 99.12%, 99.83%, 96.55% and 99.96%, respectively in ThinPrep®.
Figures and Tables
References
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