Journal List > J Korean Acad Periodontol > v.38(1) > 1049721

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Jeong, Lee, Seo, Kim, Kim, Yun, Kim, Pi, You, and Shin: Inhibitory effects of Enterococcus faecium isolated from Korean infants on oral pathogens
Original Article

The Journal of the Korean Academy of Periodontology 2008; 38(1): 31-40.

Published online: 31 March 2008

DOI: https://doi.org/10.5051/jkape.2008.38.1.31

Inhibitory effects of Enterococcus faecium isolated from Korean infants on oral pathogens

Eun-Gyeong Jeong, Jong-Cheol Lee, Jung-Yoon Seo, Seong-Yoon Kim, Wan-Su Kim, Woo-Hyuk Yun, Yun-Sang Kim, Sung-Hee Pi, Hyung-Keun You, Hyung-Shik Shin

Department of Periodontology, School of Dentistry, Wonkwang University, Korea.

Correspondence: Dr. Shin Hyung-Shik. Department of Periodontology, School of Dentistry, Wonkwang University, 344-2 Sinyong-Dong, Iksan City, Jeollabukdo, South Korea, 435-035. periohs@wonkwang.ac.kr, Tel:82-63-859-2967, Fax: 82-63-857-6364

Received 16 January 2008       Accepted 29 February 2008

Copyright © 2008 Korean Academy of Periodontology

Abstract

Purpose

The probiotic effects of lactic acid bacteria have widely been researched in diverse human pathogens, but only a few effects are reported against oral pathogens. The antimicrobial effects of the Enterococcus faecium 7413 isolated from Korean infants on the 9 pathogen including 6 oral streptococci were investigated the clinical use of the antimicrobial peptide for oral microflora control.

Materials and Methods

E. faecium 7413 was identified by morphological, biochemical tests and 16S rDNA sequence analysis. Inhibitory effects of culture supernatants were determined for their ability to grow on agar plate containing pathogenic bacteria.

Result

The culture supernatant of Enterococcus faecium 7413 showed inhibitory effects on oral pathogens, namely Streptococcus pyogenes KCTC 3556, S. pneumoniae KCTC 5080, S. mutans ATCC 25175, S. anginosus ATCC 33397, S. constellatus KCTC 3268, S. intermedius ATCC 27823 and Shigella flexneri KCTC 2008. Whereas it did not affect the multiplication of E. coli strains, KCTC 1041 and ATCC 43894.

Conclusion

The data obtained in this study could be useful for future development of effective probiotics allowing prevention for oral pathogens.

Keywords: Enterococcus faecium, infant, oral pathogens

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