Journal List > J Korean Acad Periodontol > v.35(4) > 1049540

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Han, Jung, Hyun, Kim, Kim, Pi, and Shin: Clinical study on therpeutic effects of Guided tissue regeneration by Nanogide-C® and Biomesh® in furcation defects
Original Article

The Journal of the Korean Academy of Periodontology 2005; 35(4): 877-889.

Published online: 31 December 2005

DOI: https://doi.org/10.5051/jkape.2005.35.4.877

Clinical study on therpeutic effects of Guided tissue regeneration by Nanogide-C® and Biomesh® in furcation defects

Kyung-Hee Han, Jong-Won Jung, Ha-Na Hyun, Ji-Man Kim, Yun-Sang Kim, Sung-Hee Pi, Hyung-Shik Shin

Department of Periodontology, School of Dentistry, Wonkwang University, Korea.

Copyright © 2005 Korean Academy of Periodontology

Abstract

This study was designed to compare the effects of treatment using chitosan membrane (Nanogide-C®) resorbable barrier with control treated by polylactic acid/polylacticglycolic acid membrane(PLA/PLGA membrane, Biomesh®). 44 furcation defecs from 44 patients with class 2 furcation degree were used for this study, 22 sites of them were treated by chitosan membrane as experimental group and 22 site were treated by PLA/PLGA membrane as control group. Clinical parameters including probing depth, gingival recession, attachment level and radiographic examination were evlauated at base line, 1 month, 2 month and 3 month. after surgery. Statistical test used to analyze these data included paired t-test, one way ANOVA.
The results are as follows:
1. Probing depth was significanlly decreased in the two group and there were significant differences between groups(p<0.05).
2. Gingival recession was not significanlly increased in the two group and there were no significant differences between groups(p<0.05).
3. Loss of attachment was statistically decreased in the two group and there were no significant differences between groups(p<0.05).
4. Horizontal bone level was significanlly increased in the two group and there were significant differences between groups(p<0.05).
On the basis of these results, chitoans resorbable membrane has similar potential to PLA/PLGA membrane in GTR for furcation defect.

Keywords: chitosan membrane, PLA/PLGA, furcation involvement, GTR

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