Journal List > J Korean Acad Periodontol > v.35(1) > 1049485

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Jung, Lim, Chung, Hong, and Lee: Clinical and histopathological study using platelet-rich plasma and bone graft in the localized alveolar bone defects
Original Article

The Journal of the Korean Academy of Periodontology 2005; 35(1): 251-261.

Published online: 31 March 2005

DOI: https://doi.org/10.5051/jkape.2005.35.1.251

Clinical and histopathological study using platelet-rich plasma and bone graft in the localized alveolar bone defects

Ui-Young Jung1, Sung-Bin Lim1, Chin-Hyung Chung1, Ki-Seok Hong1, Chong-Heon Lee2

1Department of Periodontology, College of Dentistry, Dan-Kook University, Korea.

2Department of Pathology, College of Dentistry, Dan-Kook University, Korea.

Corresponding author (boneperi@dankook.ac.kr)

Copyright © 2005 Korean Academy of Periodontology

Abstract

Alveolar ridge defects may limit or restrict placement of implants. The purpose of this study was to evaluate clinical and histopathologic results which occur following guided bone regeneration using platelet-rich plasma, bovine bone powder and e-PTFE membrane in the localized alveolar bone defects.
Ten patients who required guided bone regeneration in implant placemnet, were slelected. Alveolar crest height and width were measured at baseline and, afer 2nd surgery 5 months later
At 5 months, we obtained histopathological results as follows:
1. Alveolar crest height was an average of 8.20±3.74 mm preoperatively and decreased to an average of 7.40±1.84 mm postoperatively. There was no significant difference.
2. Alveolar crest width was an average of 4.25±2.03 mm preoperatively and significantly increased to an average of 7.20±2.44 mm postoperatively (P<0.01)
3. The change of Alveolar crest height and width were 0.80±1.40 mm, 2.95±1.09 mm
4. Histopathological evaluations revealed new bone formation with graft material and laminated bone containing the presence of osteocyte-like cell
In conclusion, guided bone regeneration using platelet-rich plasma, bovine bone powder and e-PTFE membrane would provide a viable therapeutic alternative for implant placement in the localized alveolar defect or implant failure

Keywords: Patelet-rich plasma, bone graft, bone defects, e-PTFE membrane

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