Journal List > J Korean Acad Periodontol > v.34(3) > 1049442

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Lee, Kim, Yun, Jung, Kim, Choi, Cho, Chai, and Kim: Clinical effect of enamel matrix derivative(EMD) in the treatment of periodontal intrabony defects
Original Article

The Journal of the Korean Academy of Periodontology 2004; 34(3): 593-605.

Published online: 30 September 2004

DOI: https://doi.org/10.5051/jkape.2004.34.3.593

Clinical effect of enamel matrix derivative(EMD) in the treatment of periodontal intrabony defects

Kyung-Jin Lee, Min-Jung Kim, Jeong-Ho Yun, Ui-Won Jung, Chang-Sung Kim, Seong-Ho Choi, Kyoo-Sung Cho, Jung-Kiu Chai, Chong-Kwan Kim

Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Brain Korea 21 Project for Medical Science, Yonsei University, Korea.

Copyright © 2004 Korean Academy of Periodontology

Abstract

Attachment level was changed from 8.67±1.72mm to 7.00±1.60mm (control); from 8.93±2.23mm to 6.00±1.92mm (test); and bone probing depth was decreased from 10.20±1.90mm to 9.07±1.95mm (control); from 10.14±2.14mm to 7.43±2.06mm (test).
This study indicates that treatment of periodontal intrabony defects with EMD is clinically superior to treatment without EMD (OFD alone) in every parameter evaluated. Within the limits of this study, the application of EMD in intrabony defects resulted in clinically significant gain of clinical attachment level and decrease of bone probing depth. And further controlled clinical studies are required to confirm the effectiveness of the EMD in the treatment of various osseous defects.

Keywords: enamel matrix derivative, periodontal regeneration, acellular cementum, clinical attachment level, probing pocket depth

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