This study evaluated above materials for periodontal regeneration of 6mm intrabony defects in 36 patients. Flap surgery was carried in 14 defects of control group. experimental group 1 was 11 defects grafted with calcium carbonate, experimental group 2 was 11 defects which were grafted with calcium carbonate with FFSS. The clinical parameters evaluated included changes in attachment level, probing depth, gingival recession at 6 months. Postsurgery probing depth reduction was 3.1 ± 0.9mm in control, 3.8 ± 1.6mm in experimental group 1, 4.1 ± 1.1mm in experimental group 2. The result clinically and statistically improved compared to baseline(P<0.01), but the difference found among the groups were not statistically significant. Postsurgery clinical attachment level was 1.6 ± 1.2mm in control, 3.5 ± 2.0mm in experimental group 1, 3.3 ± 1.2mm in experimental group 2. All of the control and experimental groups resulted in a statistically significant reduction from baseline(P<0.01). The reduction of the experimental groups were statistically significant from control(P<0.05). But the change between experimental group 1 and experimental group 2 was not statistically significant.

We conclude that mixture of CC and FFSS is effective to periodontal regeneration in intrabony defect.