Journal List > J Korean Acad Periodontol > v.32(1) > 1049283

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Kim, Choi, Chung, Han, and Ku: Antimicorbial effect of Zea Mays L. and Magnoliae cortex extract mixtures on periodontal pathogen and effect on human gingival fibroblast cellular activity
Original Article

The Journal of the Korean Academy of Periodontology 2002; 32(1): 249-255.

Published online: 31 March 2002

DOI: https://doi.org/10.5051/jkape.2002.32.1.249

Antimicorbial effect of Zea Mays L. and Magnoliae cortex extract mixtures on periodontal pathogen and effect on human gingival fibroblast cellular activity

Tae-Il Kim1, Eun-Jeong Choi2, Chong-Pyoung Chung1, Soo-Boo Han1, Young Ku1

1Department of Periodontology, College of Dentistry, Seoul National University, Korea.

2Department of Dentistry, School of Medicine, Eulji University, Korea.

Copyright © 2002 Korean Academy of Periodontology

Abstract

Zea Mays L. has been known to be effective for improving tissue health and Magnoliae cortex to have effective antibacterial and antimicrobial activity against pathogenic microbes. The purpose of this study was to examine the antimicrobial effects of Zea Mays L. and Magnoliae cortex extract mixtures on periodontal pathogens(Prevotella intermedia, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Streptococcus mutans)and to examine the effects on human gingival fibroblast cellular activity.
Zea Mays L. and Magnoliae cortex extracts and their mixtures were prepared with various mixing ratios (0.5:1, 1:1, 1.5:1, 2:1). These extracts were loaded to periodontal pathogen cultured petri dish for antimicrobial test and also loaded to cultured human gingival fibroblast for cellular activity test. Each test was repeated 3 times and data were analyzed by one-way ANOVA with 95% confidence level.
Mixture of these two extracts showed greater amount of inhibition area on periodontal pathogen and more improved gingival fibroblast activity as Zea Mays L. ratio reduced. So, mixture ratio 0.5:1 (Zea Mays L. : Magnoliae cortex) group showed statistical significance in antimicrobial activity and cellular activity among various mixtures(p<0.05).
In conclusion, 0.5:1 (Zea Mays L. : Magnoliae cortex) mixture possessed best gingival fibroblast cellular activity and antimicrobial activity toward periodontal pathogens.

Keywords: Natural extract, Magnoliae cortex, Zea Mays L., Antimicrobial effect, Cellular activity

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