Journal List > J Korean Acad Periodontol > v.27(3) > 1048976

J Korean Acad Periodontol. 1997 Sep;27(3):597-602. Korean.
Published online September 30, 1997.
Copyright © 1997 Korean Academy of Periodontology
Periodontal treatment of a Glanzmann's thrombasthenia patient: A case report
Hak Churl Lee, Soo Boo Han, Woo Sung Kim and Hye Ja Lee
Department of Periodontology, School of Dentistry, Seoul National University, Korea.

Glanzmann's thrombasthenia is a qualitative platelet disorder characterized by a deficiency in the platelet membrane glycoproteins IIb/IIIa. It belongs to a group of hereditary platelet disorders typified by normal platelet numbers and a prolonged bleeding time. The severity of bleeding does not correlate with the severity of the platelet glycoprotein IIb/IIIa abnormality.

The present case report describes the periodontal treatment of a patient with Glanzmann's thrombasthenia. A 30-year-old female with a history of Glanzmann's thrombasthenia was referred for gingival bleeding on tooth brushing and discomforts in #38 area. The periodontal finding revealed a diagnosis of localized slight adult periodontitis. Root planing and extraction of #38 was performed under 12 pack of platelets transfusion and digital compression was done for hemostasis. The gingival bleeding ceased within a day in maxilla and 2 days later in mandible. 42 pack of platelets was administered for 3 days of post-treatment and for iron-deficiency anemia 3 pack of RBCs was transfused 2 days later. 1 week later the inflammation in gingiva disappeared and gingival stippling appeared.

The clinical result we got was good and in such a medically compromised patient it is an ability to maintain a proper oral hygiene that is essential both for oral and systemic health.

Keywords: thrombasthenia; Glanzmann's; blood platelet disorder; glycoproteins