Journal List > Ann Dermatol > v.9(4) > 1046928

Ann Dermatol. 1997 Oct;9(4):239-241. English.
Published online November 28, 2016.  https://doi.org/10.5021/ad.1997.9.4.239
Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology
Analysis of Serum Zinc and Copper Levels in Alopecia Areata
Sung Yul Lee, Kee Soon Nam, Yong Won Seo, Jong Suk Lee and Hyun Chung
Abstract

Background

As co-factors of metalloenzymes, zinc(Zn) and copper(Cu) have a considerable effect on nearly all the metabolism that takes place in organs of the body, including the skin.

Objective

The purpose of this study was to evaluate zinc and copper status in alopecia areata patients.

Methods

We measured serum levels of zinc and copper in 30 cases of alopecia areata patients and 10 normal individuals by atomic absorption spectrometry. Furthermore, we studied the significance of the ratio between serum levels of the two metals.

Results

The serum levels of zinc were significantly lower in alopecia areata patients than in healthy controls. The serum levels of copper were slightly lower in alopecia areata patients than in healthy controls. Ratios of Cu/Zn were slightly higher in alopecia areata patients than in healthy controls. But their differences were not statistically significant.

Conclusion

We suggest that a serum Zn assay should be included in the chemical assessment of patients with alopecia areata.

Keywords: Aiopecia areata; Serum copper; Serum zinc