Journal List > Ann Dermatol > v.7(3) > 1046783

Kim and Park: New Combination Therapy for Vitiligo: An Effective and Short Term Regimen

Abstract

Background

The main therapeutic method currently used for the treatment of vitiligo vulgaris is either photochemotherapy or corticosteroids. But both of the procedures however require lengthy treatment to obtain a satisfactory result.

Objective

To determine the increased efficacy of the combination therapy of photochemotherapy with corticosteroid and chlorpromazine compared with the usual monotherapy.

Methods

The combination therapy was done in 29 cases and the results were compared with the results of either monotherapy appearing in the literatures.

Results

f the 29 patients, 14(48.3%) patients achieved 100% repigmentation, 7(24.1%) patients 75~50%, 5(17.2%) patients 25~50%, and 3(10.4%) patients less than 25%. For the cured patients, 190.3 days and 32.7 times of photochemotherapy were used.

Conclusion

The combination therapy is more effective, and the duration of treatment can be greatly reduced compared with either monotherapy.

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