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Chun, Kim, Song, Ro, and Chang: Acquired Reactive Perforating Collagenosis of Diabetes Mellitus and Chronic Renal Failure
Case Report

Annals of Dermatology 1990; 2(1): 43-46.

Published online: 28 November 2016

DOI: https://doi.org/10.5021/ad.1990.2.1.43

Acquired Reactive Perforating Collagenosis of Diabetes Mellitus and Chronic Renal Failure

Tae Jin Chun, Myeung Nam Kim, Kye Yong Song, Byung In Ro, Chin Yo Chang

Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology

Abstract

We report, herein, a case of reactive perforating collagenosis in a 52-year-old man with diabetes mellitus and chronic renal failure on hemodialysis. He had multiple, pinhead to pea sized, round or oval shaped, central umbilicated papules on the face, trunk, and extremities for 3 months duration. The papules developed after scratching due to pruritus.
Histopathologic examination showed a cup-shaped depression of the epidermis filled with parakeratotic material, necrobiotic collagen and inflammatory cells. At the base of the depression, the epidermis showed interruption through which basophilic bundles of collagen ex-tend in a vertical direction from the dermis.
The skin lesions improved after treatment with oral antihistaminics:

Keywords: Chronic renal failure, Diabetes mellitus, Reactive perforating collagenosis

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