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Cho, Lee, Hong, and Ro: Two Cases of Basal Cell Carcinoma Treated with Recombinant Alpha-2 Interferon
Case Report

Annals of Dermatology 1990; 2(2): 141-144.

Published online: 28 November 2016

DOI: https://doi.org/10.5021/ad.1990.2.2.141

Two Cases of Basal Cell Carcinoma Treated with Recombinant Alpha-2 Interferon

Yoon Whoa Cho, Joo Hyeup Lee, Chang Kwun Hong, Byung In Ro

Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology

Abstract

Two patients with basal cell carcinoma (BCC) were treated with recombinant alpha-2 interferon. One patient was a 48-year-old man who had a 8 × 5 an sized ulcer with an elevated border on the face for 10 years, which revealed BCC of the solid type, histopathologically. He received intralesional injections of recombinant alpha-2 interferon (total dose: 51 × 106 IU) for 11 weeks. The biopsy specimen after completion of injections showed a remaining small tumor cell nest in the lesion despite clinical remission.
The other patient was a 75-year-old female, who had 1.2 × 1.2 cm-sized, darkly pigmented, nodular BCC of the solid type on the nose for 3 years. She also received intralesional injections of recombinant alpha-2 interferon (total dose: 18 × 106 IU) for 8 weeks. The biopsy specimen after completion of injections did not show any tumor cells.

Keywords: Basal cell carcinoma, Recombinant alpha-2 interferon

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