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Park, Houh, Oh, Kim, and Kim: The Effect of pH on Sodium Lauryl Sulfate Irritancy Potential
Original Article

Annals of Dermatology 1990; 2(1): 13-16.

Published online: 28 November 2016

DOI: https://doi.org/10.5021/ad.1990.2.1.13

The Effect of pH on Sodium Lauryl Sulfate Irritancy Potential

Soo Keun Park, Dong Houh, Yung Jin Oh, Kyung Ok Kim, Chung Won Kim

Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology

Abstract

Five volunteers received patch tests with 5% sodium lauryl sulfate (SIS) in solutions of differing pH. The irritant effect was monitored by visual scoring as well as by a laser Doppler vlelocimeter, evaporimeter, cutometer, and colorimeter.
The non-invasive methods used in this study with the exception of the cutometer were effective in the evaluation of skin irritation. No significant differences in the skin responses to SIS in different pH solutions were found either clinically or by the non-invasive methods used for quantification. It was concluded that the pH of SIS is not a major factor in the degree of skin irritation produced by SIS.

Keywords: Colorimeter, Cutometer, Evaporimeter, Laser Doppler velocimeter, pH, Sodium lauryl sulfate

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