With its nerve blocking effects, intralesional injection (ILI) is a treatment method commonly used for controlling inflammation and pain syndromes in zoster patients. We herein report a case of chronic subcutaneous disease in a 52-year-old female patient caused by Mycobacterium fortuitum. Clinically, the lesion was arranged in a linear fashion, coinciding with the previous zoster site where we performed an ILI. Incision and drainage of the individual abscess pockets, with subsequent ingestion of antibiotics, was effective in our patient.