Chronic radiodermatitis may develop after repetitive exposure to small doses of ionizing radiation over an extensive period of time. Therefore, it is most likely to occur in people who work with ionizing radiation. The clinical symptoms of chronic radiodermatitis include atrophy, telangiectasia, sclerosis, pigmentary changes of the skin, ulceration and the development of malignancy. Cases of chronic radiodermatitis have occasionally been reported in physicians performing interventional procedures. Herein, we report a case of chronic radiodermatitis involving the 4th finger web and 5th finger of a radiologist, who suffered from chronic myelogenous leukemia shortly afterwards. The lesion on the 5th finger eventually progressed into squamous cell carcinoma.