The vascular involvement is seen in 8% to 24% of patients with Behcet's syndrome. Arterial lesions are less frequently observed and the involvement of renal artery is very rare. Indeed, there is only one case report of ruptured renal aneurysm due to Behc et`s disease. We report a case of renal artery rupture, which was likely caused by Behcet's disease. Even though we cannot completely rule out the other causes of renal artery rupture with this patient, the rupture was likely due to vascular involvement of Behcet's disease. Dermatologists always should consider the possibility of major vessel involvement when they treat patients with Behcet's disease, even if the incidence is very low and the patient may not complain of any systemic symptoms.