Journal List > Ann Dermatol > v.12(2) > 1044619

TOOLS
Song, Park, and Lee: Three Cases of Livedoid Vasculitis Improved by Low-dose Danazol
Original Article

Annals of Dermatology 2000; 12(2): 134-137.

Published online: 16 March 2016

DOI: https://doi.org/10.5021/ad.2000.12.2.134

Three Cases of Livedoid Vasculitis Improved by Low-dose Danazol

Min Gyu Song, Soo Hong Park, Eil Soo Lee

Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology

Abstract

Livedoid vasculitis is characterized clinically by smooth or depressed ivory-white scars surrounded by hyperpigmentation and telangiectasia with or without preceding purpuric in-filtrated papules and plaques and histologically by intravascular deposition of fibrin. Its pathophysiology is still obscure. Many treatment modalities have been used, but results are not satisfactory.
Recently, there have been experiences of successful treatments with danazol, a synthetic androgen. We used danazol in three patients who presented with livedoid vasculitis and were relatively resistant to treatments with aspirin and/or pentoxifylline. After 4 to 8 weeks, there was remarkable clinical improvement in all three patients.

Keywords: Danazol, Livedoid vasculitis

TOOLS
Similar articles