Analysis of Histopathologic Characteristic and Treatment of Sinonasal Benign Tumor

Junhui Jeong; Hyo Jin Chung; Joo-Heon Yoon; Jeung-Gweon Lee; Chang-Hoon Kim

doi:10.18787/jr.2017.24.2.81

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Jeong, Chung, Yoon, Lee, and Kim: Analysis of Histopathologic Characteristic and Treatment of Sinonasal Benign Tumor

Original Article

Journal of Rhinology 2017; 24(2): 81-88.

Published online: 30 November 2017

DOI: https://doi.org/10.18787/jr.2017.24.2.81

Analysis of Histopathologic Characteristic and Treatment of Sinonasal Benign Tumor

Junhui Jeong, MD¹, Hyo Jin Chung, MD¹, Joo-Heon Yoon, MD, PhD², Jeung-Gweon Lee, MD, PhD², Chang-Hoon Kim, MD, PhD²

¹Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.

²Department of Otorhinolaryngology, College of Medicine, Yonsei University, Seoul, Korea.

Corresponding author (entman@yuhs.ac)

Received 27 June 2016 Revised 8 March 2017 Accepted 22 April 2017

Journal of Rhinology

Abstract

Background and Objectives

The main treatment modality of sinonasal benign tumor is surgical resection, and the endoscopic intranasal approach has been commonly performed since the 1990s. The objective of this study was to evaluate the recurrence rates of different sinonasal benign tumors and to analyze the diverse approaches used in their surgical treatment.

Subjects and Method

In 270 patients who were histopathologically diagnosed with sinonasal benign tumor during a period of 20 years, histopathologic type, treatment approach, interval between first treatment and recurrence, and recurrence rate according to treatment approach were analyzed.

Results

Recurrence rate was higher with the intranasal approach than with the extranasal approach in inverted papilloma and angiofibroma, but the differences were not statistically significant. The proportion of the intranasal approach during the latter 10 years was higher than that during the former 10 years. There was no significant differences between the recurrence rate during the former 10 years and that during the latter 10 years for both intranasal and extranasal approaches.

Conclusion

Based on tumor location and stage and skill of the surgeon, the intranasal approach can replace the extranasal approach with no major changes in treatment outcome.

Keywords: Nasal cavity, Paranasal sinuses, Nose neoplasms, Paranasal sinus neoplasms

Figures and Tables

Table 1

Histopathologic type of sinonasal benign tumor in this study

*: Proportion of each histopathologic type to total benign tumor

Table 2

Recurrence rate of inverted papilloma according to treatment approach

*: Intranasal approach includes endoscopic approach, microscopic approach, laser vaporization, and modified Denker's operation

Table 3

Recurrence rate of angiofibroma according to treatment approach

*: All patients of angiofibroma are male, †: Intranasal approach includes endoscopic approach and microscopic approach

Table 4

Recurrence rate of inverted papilloma according to treatment approach during former 10 years and latter 10 years

*: Patients whose diseases recurred after each period were censored, †: Base period was set on January 1st, 2,000, former 10 years range from January 1st, 1990 until December 31st, 1999 and latter 10 years range from January, 1st 2,000 until December 31st, 2009, ‡: Intranasal approach includes endoscopic approach, microscopic approach, laser vaporization, and modified Denker's operation

Table 5

Interval between first treatment and recurrence in inverted papilloma

*: Intranasal approach includes endoscopic approach, microscopic approach, laser vaporization, and modified Denker's operation

Table 6

Interval between first treatment and recurrence in angiofibroma

*: All patients of angiofibroma are male, †: Intranasal approach includes endoscopic approach and microscopic approach

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