Journal List > J Rhinol > v.22(2) > 1044331

Lee, Lee, Cho, and Lim: Mucocele of the Nasal Septum: Case Report and Review of the Literature


Mucoceles are relatively common cystic lesions of the paranasal sinuses. However, mucocele of the nasal septum is extremely rare. We report a case of a mucocele present in this unusual location. Mucocele of the nasal septum should be considered in the differential diagnosis of a mass of the nasal septum and/or median canthal region. Nasal septal mucocele can be effectively treated with endoscopic marsupialization or complete excision.


1). Lee YB, Lee KC, Lee JW, Jin SM. A case of a sphenoid sinus mucocele protruding into both nasal cavities: transnasal endoscopic marsupialization. J Rhinol. 1999; 6(1):75–8.
2). Gall R, Witterick I. Mucocele of the nasal septum. J Otolaryngol. 2002; 31(4):246–7.
3). Lei L, Wang R, Han D. Pneumatization of perpendicular plate of the ethmoid bone and nasal septal mucocele. Acta Otolaryngol. 2004; 124(2):221–2.
4). Taskin U, Korkut YA, Aydin S, Oktay FM. Atypical presentation of primary giant nasal septal mucopyocele. J Craniofac Surg. 2012; 23(1):5–7.
5). Friedmann DR, Roman B, Lebowitz RA, Bloom JD. Radiology quiz case 2. Diagnosis: intraseptal mucocele. JAMA Otolaryngol Head Neck Surg. 2013; 139(6):647–8.
6). Lee KC, Lee NH. Comparison of clinical characteristics between primary and secondary paranasal mucoceles. Yonsei Med J. 2010; 51(5):735–9.
7). Stankiewicz JA, Newell DJ, Park AH. Complications of inflammatory diseases of the sinuses. Otolaryngol Clin North Am. 1993; 26(4):639–55.
8). Lund VJ, Milroy CM. Fronto-ethmoidal mucoceles: a histopathological analysis. J Laryngol Otol. 1991; 105(11):921–3.
9). Soon SR, Lim CM, Singh H, Sethi DS. Sphenoid sinus mucocele: 10 cases and literature review. J Laryngol Otol. 2010; 124(1):44–7.

Fig. 1.
Endoscopic examination shows a submucosal mass (as-terisk) on the left nasal septum (S).
Fig. 2.
Enhanced CT of the paranasal sinuses (A) revealed a 1.5 cm sized high attenuated cystic mass (arrow) in the left nasal septum. On MRI, a mass (arrow) on the left nasal septum had high signal on T1-weighted image (B) and low signal on T2-weighted image (C), suggesting a mucocele.
Fig. 3.
(A) Intraoperative appearance of left nasal cavity following endoscopic marsupialization (B) At 3months’ follow up, endoscopic examination shows a well marsupialized cavity on the left nasal septum.
Fig. 4.
Histopatholgoic examination shows that a cyst is lined by low cuboidal epithelium and little inflammatory cells (Hematoxylin & Eosin staining, ×200).
Table 1.
Summary of previously reported cases with nasal septal mucocele
Cases (n=5) Age/ Gender r Presenting symptoms Facial appearance Endoscopic findings Treatment outcome Complication Follow-Up (Months)
Gall et al.1) 62/M Bilateral NO Swelling at the lateral border of the nose and medial canthus Bilateral septal swelling Endoscopic marsupialization (NED) None 02
Lei et al.2) 37/M Increasing nasal mass and pain Nasal mass Bilateral buldging of upper septum Endoscopic excision (NED) None 10
Taskin et al.3) 45/M Bilateral NO Swelling at the medial canthus bilateral swelling of the septum Endoscopic excision (NED) None ND
Friedmann et al.4 4)32/M Bilateral NO Widening of the nasal vault and dorsum Bilateral submucosal septal mass Endoscopy assisted external approach and excision (NED) ND ND
Present case 52/F Headache NS Unilateral swelling of the septum Endoscopic marsupialization (NED) None 16

NO: nasal obstruction, NS: nonspecific, NED: no evidence of disease, ND: not described

Similar articles