Journal List > Hanyang Med Rev > v.32(3) > 1044118

Park and Choi: Clinical Applications of Neural Stem Cells for the Treatment of Peripheral Neuropathy

Abstract

Extraordinary advances in stem cell research have initiated an era of hope for strategies to treat intractable human diseases. Personalized regenerative treatment using stem cells is expected to accelerate continuous investment and research efforts throughout the world. Despite of their constraints, adult stem cells and embryonic stem cells have been used for cell transplantation for several intractable diseases. Besides adult and embryonic stem cells, the recent studies of induced pluripotent stem cells widened the possibility of patient-specific cell therapy, drug discovery, and disease modeling. This review focuses on the developments and potential applications of the stem cells for the treatment of peripheral neuropathy.

Figures and Tables

Fig. 1
Preparation of induced pluripotent stem cells for Charcot-Marie-tooth disease. (A) control human fibroblast, (B) control human lymphocyte, (C) Charcot-Marie-Tooth patient fibroblast (Original magnification×100).
hmr-32-154-g001

ACKNOWLEDGMENTS

This study was supported by the grant of the National Project for Personalized Genomic Medicine, Ministry for Health & Welfare, Republic of Korea (A111218-GM07), and the Ewha Global Top 5 Grant 2011 of Ewha Womans University.

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