Journal List > Hanyang Med Rev > v.29(3) > 1044022

Rho: Surgical Management of Sinonasal Cancer

Abstract

Sinonasal cancers account for less than 1% of all malignancies and comprise 3% of all head and neck malignancies. The most common malignant neoplasm in the sinuses and nose is squamous cell carcinoma, which accounts for 70% of these neoplasms. Most of these arise in the maxillary antrum, and only 10% to 30% occur in the nasal cavity or ethmoid sinus.
It is well known the surgery is primary treatment for sinonasal malignancies. Adjunctive irradiation and/or chemoradiatioin has resulted in improved locoregional control and increased survival rates. The goal of surgical resection is to remove the cancer en bloc, with clear margin devoid of neoplastic cells. For maxillary sinus neoplasms, maxillectomy is a standard surgical procedure. Neoplasms involving the ethmoid, frontal, or sphenoid sinuses may require a craniofacial approach because of frequent invasion into the skull base.
The proximity of the nasal cavity and paranasal sinuses to the adjacent structures including the orbit, dura, brain, cranial nerves, and carotid arteries mandates careful radiologic and neurologic evaluations throughout the course of the disease. Surgical advances now permit complex tumor removal and reconstruction surrounding these structures resulting in functional and cosmetic improvements when compared to earlier techniques.

Figures and Tables

Fig. 1
The various facial incision for maxillectomy is illustrated.
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Fig. 2
Intraoperative photograph of the partial maxillectomy. (a) Infrastructure maxillectomy (b) Medial maxillectomy, (c) Suprastructure maxillectomy.
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Fig. 3
The osteotomies required for a total maxillectomy and Intraoperative photograph of the total maxillectomy defect.
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Fig. 4
Axial and coronal CT scans demonstrate poor prognostic factors in sinonasal cancer. (a) Intracranial extension (dura, brain), (b) Orbital invasion, (c) Extension to pterygoid plates, infratemporal fossa, nasopharyngeal extension.
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Fig. 5
Coronal CT scan and axial MRI view accurately demonstrate the extent of orbit invasion from left-sided maxillary sinus tumor.
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Fig. 6
Intraoperative photograph of the radical maxillectomy with pterygoid extension (a) Lateral extension of lateral canthotomy incision. (b) Ligation of the internal maxillary artery. (c) Posterior osteotomy behind the pterygoid plate.
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Fig. 7
Standard subfrontal approach.
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Table 1
Pathologic distribution of sinonasal cancer in HUMC
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Abbreviation : HUMC, Hallym university medical center

Table 2
Classification of surgical management in sinonasal cancer
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Table 3
Type of maxillectomy for primary sinonasal cancer in HUMC
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Table 4
Comparison of local recurrence after surgery in suspicious orbital invasion on CT and MRI images
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Table 5
Various transcranial approach
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Table 6
Complication after craniofacial resection in HUMC
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Table 7
Methods of orbital wall reconstruction
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Table 8
Failure pattern of primary sinonasal cancer in our institute
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References

1. Resto VA, Deschler DG. Sinonasal malignancies. Otolaryngol Clin North Am. 2004; 37:473–487.
crossref
2. Dulguerov P, Jacobsen MS, Allal AS. Nasal and paranasal sinus carcinoma: are we making progress? A series of 220 patients and a systematic review. Cancer. 2001; 92:3012–3029.
crossref
3. Lee MM, Vokes EE, Rosen A. Multimodality therapy in advanced paranasal sinus carcinoma: superior long-term results. Cancer J Sci Am. 1999; 5:219–223.
crossref
4. Jho HD, Ha HG. Endoscopic endonasal skull-base surgery: part 1-the midline anterior fossa skull base. Minim Invasive Neurosurg. 2004; 47:1–8.
crossref
5. Jho HD, Ha HG. Endoscopic endonasal skull-base surgery: part 2-the cavernous sinus. Minim Invasive Neurosurg. 2004; 47:9–15.
6. Lund VJ, Howard DJ, Wei WI, Cheesman AD. Craniofacial resection for tumors of the nasal cavity and paranasal sinuses. A 17-year experience. Head Neck. 1998; 20:97–105.
crossref
7. Roh HJ, Moon YI. Endoscopic Surgery for Sinonasal tumor. J Clin Otolaryngol Head Neck Surg. 2002; 13:165–171.
crossref
8. Batra PS, Citardi MJ. Endoscopic management of sinonasal malignancy. Otolaryngol Clin North Am. 2006; 39:619–637.
crossref
9. Sisson GA. Symposium III. Treatment of malignancies of paranasal sinuses : Discussion and summary. Laryngoscope. 1970; 80:945–953.
10. Carrau RL, Segas J, Nuss DW. Squamous cell carcinoma of the sinonasal tract invading the orbit. Laryngoscope. 1999; 109:230–235.
crossref
11. Ji YB, Song MN, Sung YS, Lee YS, Kim KB, Tae K. The significance of orbital preservation in surgery of the sinonasal malignancies. Korean J Otorhinolaryngol-Head Neck Surg. 2009; 52:349–353.
crossref
12. Raveh J, Turk JB, Ladrach K. Extended anterior subcranial approach for skull base tumors: long-term results. J Neurosurg. 1995; 82:1002–1010.
crossref
13. Moore CE, Ross DA, Marentette LJ. Subcranial approach to tumors of the anterior cranial base: analysis of current and traditional surgical techniques. Otolaryngol Head Neck Surg. 1999; 120:387–390.
crossref
14. Ganly I, Patel SG, Singh B. Craniofacial resection for malignant paranasal sinus tumors: report of an international collaborative study. Head Neck. 2005; 27:575–584.
crossref
15. Suarez C, Llorente JL, Fernandez de Leon R, Maseda E. Prognostic factors in sinonasal tumors involving the anterior skull base. Head Neck. 2004; 26:136–144.
crossref
16. Day TA, Davis BK. Skull-base reconstruction and rehabilitation. Otolaryngol Clin North Am. 2001; 34:1241–1257.
17. Le QT, Fu KF, Kaplan MJ. Lymph node metastasis in maxillary sinus carcinoma. Int J Radiat Oncol Biol Phys. 2000; 46:541–549.
crossref
18. Kim GE, Chung EJ, Lim JJ. Clinical significance of neck node metastasis in squamous cell carcinoma of the maxillary antrum. Am J Otolaryngol. 1999; 20:383–390.
crossref
19. Cordeiro PG, Disa JJ. Challenges in midface reconstruction. Semin Surg Oncol. 2000; 19:218–225.
crossref
20. Carrillo JF, Guemes A, Ramirez-Ortega MC, Onate-Ocana LF. Prognostic factors in maxillary sinus and nasal cavity carcinoma. Eur J Surg Oncol. 2005; 31:1206–1212.
crossref
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