Advanced Laryngeal Cancer: Surgical and Non-surgical Management Options

Kwang Hyun Kim

doi:10.7599/hmr.2009.29.3.204

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Kim: Advanced Laryngeal Cancer: Surgical and Non-surgical Management Options

Review Article

Hanyang Medical Reviews 2009; 29(3): 204-209.

Published online: 31 August 2009

DOI: https://doi.org/10.7599/hmr.2009.29.3.204

Advanced Laryngeal Cancer: Surgical and Non-surgical Management Options

Kwang Hyun Kim, M.D., Ph.D.

Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Seoul National University, Seoul, Korea.

Corresponding author (kimkwang@plaza.snu.ac.kr)

Received 7 July 2009 Accepted 10 August 2009

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Until the early 1990s, the standard treatment for locally advanced laryngeal cancer was total laryngectomy. During the past 20 years, effort was made to save the larynx by using chemotherapy combined with radiation and there has been significant progression in survival and the preservation of the function of larynx in recent days. Now, the standard treatment option for advanced laryngeal cancer is changing from radical surgery to induction or concurrent chemoradiation and the surgery is mainly reserved for salvage operation. But, the quality of life after CCRT is sometimes unacceptable due to severe side effects and some prefer function preserving surgery. The decision for surgical or nonsurgical options needs to be made according to patient's wishes and quality of life goals from a multidisciplinary approach with medical oncologists, radiation oncologists, and head and neck surgeons. Chemoradiation therapy allows for nonsurgical management, but judicious use is recommended because the surgical salvage for failure is much more complicated.

Keywords: Laryngeal cancer, Organ preservation, Laryngectomy, Chemotherapy, Radiation

Figures and Tables

Table 1

Advanced laryngeal cancer stage according to the 6th AJCC1

Table 2

Surgical treatment options for advanced laryngeal cancer

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