Journal List > Korean J Nutr > v.43(1) > 1043820

Korean J Nutr. 2010 Feb;43(1):26-33. Korean.
Published online February 28, 2010.
© 2010 The Korean Nutrition Society
Analysis of the Factors Relating Nutritional Status in Discharging of Leukemia Patients Receiving Chemotherapy
Eunjin So, Jeeyeon Kim, Sujin Jung and Sook Park
Nutrition Department of the Catholic University of Korea Seoul St. Mary's Hospital, Seoul 137-701, Korea.

To whom correspondence should be addressed. (Email: )
Received January 04, 2010; Revised February 01, 2010; Accepted February 17, 2010.


This study was performed to investigate the changes of oral diet intake during the admission period and identify the factors related with nutritional status in discharging of leukemia patients. This is a retrospective cross sectional study on 46 leukemia patients receiving chemotherapy at the Catholic University of Korea Seoul St. Mary's Hospital from July to September 2009. The patients' charts were surveyed on the general characteristics and factors relating chemotherapy. The calorie count method was used to investigate diet intake during admission period. Multivariate logistic regression analysis was used to identify possible confounding factors. A p < 0.05 was considered statistically significant. The mean age was 42.8 ± 14.6 years and the average length of stay was 30.4 ± 7.0 days. The incidence of malnourished patients was 60.9% in discharging. There was a significant difference in chemotherapy sessions and chemotherapy period between well-nourished and malnourished patients. The average energy intake was 1,525.9 kcal in well-nourished patients and 1,143 kcal in malnourished patients, which was significant different. From repeated measures ANOVA test, the changes of oral intake during admission period were significant by groups. In addition, there were significant differences in oral intake according to each period between well-nourished and malnourished patients. In multivariate logistic regression analysis, both the ratio of total oral energy intake to recommended energy intake and chemotherapy sessions were significantly associated with nutritional status in discharging. The results of this study could be used to establish a protocol of nutritional management for leukemia patients receiving chemotherapy.

Keywords: leukemia; chemotherapy; nutritional status; energy intake


Table 1
General characteristics of subjects (n = 46)
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Table 2
Oral intake status by the nutritional status in discharging
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Table 3
Change of oral intake during chemotherapy period by the nutritional status in discharging
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Table 4
Logistic regression model for variables affecting the nutritional status in discharging
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