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Korean J Pediatr Gastroenterol Nutr. 2011 Jun;14(2):181-186. Korean.
Published online June 30, 2011.  https://doi.org/10.5223/kjpgn.2011.14.2.181
Copyright © 2011 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
A Case of Non-IgE-mediated Eosinophilic Gastroenteritis Presenting as Ascites
Eun Sang Yi, M.D., Mi Jin Kim, M.D., Sang Yun Ha, M.D.,* Yoo Min Lee, M.D., Kyong Eun Choi, M.D. and Yon Ho Choe, M.D.
Department of Pediatrics, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea.
*Department of Pathology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea.

Corresponding author (Email: yonho.choe@samsung.com )
Received April 18, 2011; Revised June 05, 2011; Accepted June 08, 2011.

Abstract

Eosinophilic gastroenteritis is a rare disease occurring especially in children, and shows various non-specific presentations with infiltration of eosinophils in the gastrointestinal organs. The pathophysiology of eosinophilic gastroenteritis is not yet clearly known, but allergic reactions are suspected to be related with the disease. Eosinophilic gastroenteritis is categorized into the mucosal, muscularis and subserosal types based on which layer of the intestinal wall is involved. There are different clinical manifestations according to the involved layer. Most cases to date have responded well to steroid therapy. In this study, we diagnosed and treated a case of non-IgE-mediated, subserosal eosinophilic gastroenteritis in a child with abdominal pain, diarrhea and ascites.

Keywords: Non-IgE-mediated; Eosinophilic gastroenteritis; Ascites

Figures


Fig. 1
The ascitic fluid shows many eosinophils.
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Fig. 2
Abdomen CT showed diffuse wall thickening of the small and large bowel.
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Fig. 3
The endoscopic biopsy findings showed a marked eosinophil infiltration in the second portion of the duodenum (A) and the rectum (B) (H&E stain, 400).
Click for larger image

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