A Case of Non-IgE-mediated Eosinophilic Gastroenteritis Presenting as Ascites

Eun Sang Yi; Mi Jin Kim; Sang Yun Ha; Yoo Min Lee; Kyong Eun Choi; Yon Ho Choe

doi:10.5223/kjpgn.2011.14.2.181

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Yi, Kim, Ha, Lee, Choi, and Choe: A Case of Non-IgE-mediated Eosinophilic Gastroenteritis Presenting as Ascites

Case Report

Korean Journal of Pediatric Gastroenterology and Nutrition

Korean Journal of Pediatric Gastroenterology and Nutrition 2011; 14(2): 181-186.

Published online: 30 June 2011

DOI: https://doi.org/10.5223/kjpgn.2011.14.2.181

A Case of Non-IgE-mediated Eosinophilic Gastroenteritis Presenting as Ascites

Eun Sang Yi, M.D., Mi Jin Kim, M.D., Sang Yun Ha, M.D.^*, Yoo Min Lee, M.D., Kyong Eun Choi, M.D., Yon Ho Choe, M.D.

Department of Pediatrics, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea.

^*Department of Pathology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea.

Corresponding author (yonho.choe@samsung.com)

Received 18 April 2011 Revised 5 June 2011 Accepted 8 June 2011

Abstract

Eosinophilic gastroenteritis is a rare disease occurring especially in children, and shows various non-specific presentations with infiltration of eosinophils in the gastrointestinal organs. The pathophysiology of eosinophilic gastroenteritis is not yet clearly known, but allergic reactions are suspected to be related with the disease. Eosinophilic gastroenteritis is categorized into the mucosal, muscularis and subserosal types based on which layer of the intestinal wall is involved. There are different clinical manifestations according to the involved layer. Most cases to date have responded well to steroid therapy. In this study, we diagnosed and treated a case of non-IgE-mediated, subserosal eosinophilic gastroenteritis in a child with abdominal pain, diarrhea and ascites.

Keywords: Non-IgE-mediated, Eosinophilic gastroenteritis, Ascites

Figures and Tables

Fig. 1

The ascitic fluid shows many eosinophils.

Fig. 2

Abdomen CT showed diffuse wall thickening of the small and large bowel.

Fig. 3

The endoscopic biopsy findings showed a marked eosinophil infiltration in the second portion of the duodenum (A) and the rectum (B) (H&E stain, 400).

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