Journal List > Korean J Pediatr Gastroenterol Nutr > v.13(1) > 1043479

Korean J Pediatr Gastroenterol Nutr. 2010 Mar;13(1):58-65. Korean.
Published online March 31, 2010.
Copyright © 2010 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
Clinical Features of Acute Pancreatitis in Children
Jung Ho Seo, M.D., Seong Heon Kim, M.D., Sang Geon Jeong, M.D.,* and Jae Hong Park, M.D.
Department of Pediatrics, School of Medicine, Pusan National University, Busan, Korea.
*Department of Pediatrics, Good Gangahn Hospital, Busan, Korea.

Responsible author (Email: )
Received February 19, 2010; Accepted March 12, 2010.



Since there are few studies involving acute pancreatitis in children, we reviewed our experience with this medical condition to describe the clinical features.


A retrospective analysis was conducted by reviewing the medical records of 41 patients with AP who were admitted to the Department of Pediatrics of Pusan National University Hospital between January 1996 and June 2007.


Twenty males and 21 females (mean age, 8.7±4.5 years) were included. In 22 patients (53.7%), no definitive causes were found. The most common etiologies were choledochal cysts (22.0%). Necrotizing pancreatitis was diagnosed in 5 patients (12.2%), and recurrent acute pancreatitis in 4 patients (9.8%). CT findings included pancreatic swelling (43.9%), peripancreatic fluid collection (29.3%), ascites (24.4%), and peripancreatic fat necrosis (12.2%). Serum amylase and lipase levels at diagnosis were 535.3±553.2 and 766.2±723.6 U/L, respectively, and were normalized within 1 week in 22 and 14 patients, respectively. On the basis of the Balthazar scale, 2 patients were diagnosed with severe AP. In 4 patients (9.8%), a surgical procedure was indicated. Major complications included ascites (32.3%), sepsis (16.1%), and pseudocyst and renal impairments (12.9%). Two patients died from multi-organ failure.


The etiologies of AP in children are varied. Most children have a single episode and a self-limited course. However, AP of childhood still carries significant morbidity and mortality. Early diagnosis, appropriate treatment according to disease severity, and management of complications are important.

Keywords: Acute pancreatitis; Children


Table 2
Presenting Symptoms on Admission
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Table 3
Etiology of Acute Pancreatitis in Children
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Table 4
Initial Laboratory Findings
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Table 5
Radiologic Findings
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Table 6
Normalization of Serum Amylase and Lipase Levels
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Table 7
Prognosis Scoring System
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