Journal List > Korean J Pediatr Gastroenterol Nutr > v.13(2) > 1043468

Korean J Pediatr Gastroenterol Nutr. 2010 Sep;13(2):164-171. Korean.
Published online September 30, 2010.
Copyright © 2010 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
Iron Deficiency Anemia and Vitamin D Deficiency in Breastfed Infants
Eun Hye Choi, M.D., Soo Ho Jung, M.D., Yong Hoon Jun, M.D., Yoo Jin Lee,* Ji Yeon Park, Jeong Soon You, Kyung Ja Chang, and Soon Ki Kim, M.D.
Department of Pediatrics, College of Medicine, Inha University, Incheon, Korea.
*Dietary Department, Health Promotion Center, Inha University Hospital, Incheon, Korea.
Department of Food and Nutrition, Inha University, Incheon, Korea.

Corresponding author (Email: )
Received August 13, 2010; Revised August 17, 2010; Accepted September 10, 2010.



Iron deficiency anemia (IDA) is one of the most common nutritional problems, despite a recent improvement of nutritional status of infants and children. We assessed the risk factors for IDA in infants and vitamin D deficiency and IDA by nutrition analysis.


We analyzed blood tests and evaluated 103 children with IDA and 123 children without IDA, 6-36 months of age, who were cared for in our hospital between March 2006 and July 2010. Nutritional analysis using Canpro was performed among breastfed infants 6~12 months of age who had been diagnosed with IDA and had detailed diet histories.


Breastfed infants accounted for 87.4% and 40.7% of the IDA and comparison groups, respectively. The IDA and comparison groups began weaning food at 6.4±1.8 and 5.9±1.3 months, respectively. In the IDA and comparison groups, 46.4% and 53.5% began to adapt to weaning food within 4 weeks, respectively. The most common reason for hospital care of the IDA group was respiratory symptoms constituting 36.2%. Only 18.6% visited the hospital for palloror anemia. The Canpro analysis, performed on 11 infants with IDA, showed that iron and vitamin D were <40% and 30% of recommended intakes, respectively.


Weaning food should be started 4~6 months of age in breastfed infants. In infants at high risk for IDA and vitamin D deficiency, screening tests should be recommended. The high-risk infants may require iron, vitamin D fortified formula, or oral supplements.

Keywords: Iron deficiency anemia; Vitamin D deficiency; Weaning food; Breastfed


Table 1
Comparison of Feeding Patterns between IDA and Comparison Groups
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Table 2
Interval from the Beginning of Weaning to the Proper Solid Food Intake
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Table 3
Chief Complaints or Diseases on Initial Visit in the IDA Group
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Table 4
Hematologic Values of the IDA and Comparison Groups
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Table 5
Weaning Food Plus Breast-fed Nutrition Composition in Children with IDA
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