Journal List > J Korean Foot Ankle Soc > v.18(3) > 1043304

Lee, Kim, and Jung: Intravascular Papillary Endothelial Hyperplasia in Foot Adherent to a Saphenous Nerve Branch: A Case Report

Abstract

Intravascular papillary endothelial hyperplasia (IPEH) has appeared in the literature under a variety of names, including Masson’s tumor, Masson’s hemangioma, and Masson’s pseudoangiosarcoma. It is a benign lesion of the skin and subcutaneous tissue characterized by reactive proliferation of vascular endothelial cells with papillary formations. The clinical picture is not specific and the lesion resembles malignant angiosarcoma clinically and histopathologically. Therefore, it is often mistaken for angiosarcoma and a group of other benign and malignant vascular lesions. We report on a case of IPEH adherent to peripheral nerve treated with operative excision.

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Figure 1.
Photograph shows a protruding mass lesion on dorsomedial aspect of right foot.
jkfas-18-129f1.tif
Figure 2.
Plain radiograph shows a round soft tissue lesion on medial aspect of medial cuneiform. There is no bony erosion or calcification.
jkfas-18-129f2.tif
Figure 3.
Ultrasonography shows an ovoid-shape, 2.2×0.7×1.4 cm size cystic mass on dorsomedial aspect of right foot. Sagittal (A) and Axial (B).
jkfas-18-129f3.tif
Figure 4.
The mass is connected to the branch of saphenous nerve proximally and distally.
jkfas-18-129f4.tif
Figure 5.
Photograph shows a dark-reddish cystic mass of 2×1×1 cm size.
jkfas-18-129f5.tif
Figure 6.
Pathologic features. (A) Myriad small delicate papillae project into the vascular lumen. The papillae are composed of a single layer of vascular endothelium surrounding a stromal core (H&E stain, ×100). (B) The vascular endothelium of papillae is well demonstrated by positive (brown) immunohistochemical reaction to CD31 antibody (immunohistochemistry stain, ×100).
jkfas-18-129f6.tif
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