Journal List > J Korean Med Assoc > v.54(9) > 1042491

TOOLS
Shim and Kim: Therapy for idiopathic precocious puberty in children
Pharmacotherapeutics
Journal of the Korean Medical Association

Journal of the Korean Medical Association 2011; 54(9): 953-956.

Published online: 15 September 2011

DOI: https://doi.org/10.5124/jkma.2011.54.9.953

Therapy for idiopathic precocious puberty in children

Kye Shik Shim, MD1, Jung Tae Kim, PhD2

1Department of Pediatrics, Kyung Hee University School of Medicine, Seoul, Korea.

2Department of Pharmacy, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Pharmacy, Seoul, Korea.

Corresponding author: Kye Shik Shim, 64sks@khnmc.or.kr

Received 27 June 2011       Accepted 10 July 2011

Copyright © 2011 Korean Medical Association

(open-access):

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The incidence of idiopathic precocious puberty is rapidly increasing in Korea. The most common medication used for treatment is a gonadotropin releasing hormone agonist. However, there is some debate regarding the indication and timing of treatment, and the dosage of the medication, because there are many factors that can affect growth in children after delaying puberty. Also, there are new medications that can potentially delay the puberty with children, for example, gonadotropin releasing hormone antagonists and aromatase inhibitors which require extensive further study.

Keywords: Precocious puberty, Gonadotropin-releasing hormone, Agonist

Figures and Tables

Figure 1
The total number and medical cost of patients with precocious puberty from 2006 through 2010 in Korea (From The early detection of precocious puberty [Internet]. Seoul: Health Insurance Review & Assessment Service; 2011) [3].
jkma-54-953-g001

References

1. Rosenfield RL, Cooke DW, Radovick S. Sperling MA, editor. Puberty and its disorders in the female. Pediatric endocrinology. 2008. 3rd ed. Philadelphia: Saunders Co;530–609.
crossref
2. Styne D, Grumbach M. Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, editors. Puberty: ontogeny, neuroendocri-nology, physiology, and disorders. Williams textbook of endocrinology. 2008. 11th ed. Philadelphia: Saunders Co;969–1166.
3. The early detection of precocious puberty [Internet]. 2011. cited 2011 Aug 10. Seoul: Health Insurance Review & Assessment Service;Available from: http://www.hira.or.kr/cms/rc/rce_news/1205871_10816.html.
4. Shim KS, Bae CW, Yang YJ. A comparative study of the pu-berty suppression effect of gonadotropin-releasing hormone agonist in precocious or early puberty girls. Korean J Pediatr. 2008. 51:634–639.
crossref
5. Jin HY, Choi JH, Yoo HW. Evaluation of efficacy of GnRH agonist on predicted adult height (PAH) in patients with central precocious puberty using two different dosages. J Korean Soc Pediatr Endocrinol. 2010. 15:120–125.
TOOLS
Similar articles