PDF
ePub
Citation
Print
Abstract
Spinal Stereotactic Radiosurgery (SRS) has become an important treatment modality for a broad range of spinal tumors and spinal vascular lesions. Recent clinical acceptance and awareness of the usefulness of spinal radiosurgery has escalated with the development of modern radiosurgical technology. Image-guided navigation systems incorporating non-invasive fiducial tracking and virtual simulation planning systems have made spinal radiosurgery increasingly effective and expanded the range of clinical applications for which it can be effectively used. Additional improvements such as Intensity Modulation and Micro-Multileaf Collimation that allow the accurate modulating and shaping of the radiation beam have also contributed greatly to the ability of clinicians to treat irregular and critically located lesions with greatly reduced collateral risk. Spinal Radiosurgery for spinal tumors can achieve similar clinical results to cranial stereotactic radiosurgery for brain tumors in terms of achieving local tumor control and improving quality of life and survival rates. Stereotactic radiosurgery, which has long been used for the treatment of intracranial lesions, is now recognized to be a viable option for treating spinal tumors and spinal vascular lesions.
Figures and Tables
Figure 1
Comparison of Kaplan-Meier Survival curve between palliapive group vs. locally curapive group.
References
1. Rock JP, Ryu S, Yin FF, Schreiber F, Abdulhak M. The evolving role of sterotactic radiosurgey and stereotactic radiation therapy for patients with spine tumors. J Neurooncol. 2004. 69:319–334.
2. Benzil DL, Saboori M, Mogilner AY, Rochhio R, Moorthy CR. Safety and efficacy of stereotactic radiosurgery for tumors of the spine. J Neurosurg. 2004. 101:413–418.
3. De Salles AA, Pedroso AG, Medin P, Agazaryan N, Solberg T, Cabatan-Awang C, Espinosa DM, Ford J, Selch MT. Spinal lesions treated with Novalis shaped beam intensity-modulated radiosurgery and stereotactic radiotherapy. J Neurosurg. 2004. 101:435–440.
4. Sohn MJ, Lee DJ, Lee HR, Whang CJ. Strategy of spinal Radiosurgery for metastatic spine tumors: curative vs. palliative treatment. J of the Kor Soc of Ster and Func Neurosurg. 2007. 3:1–8.
5. Sheehan J, Kondziolka D, Flickinger J, Lunsford LD. Radiosurgery for patients with recurrent small cell lung carcinoma metastatic to the brain: outcomes and prognostic factors. J Neurosurg. 2005. 102:S. 247–254.
6. Sheehan JP, Sun MH, Kondziolka D, Flickinger J, Lunsford LD. Radiosurgery in patients with renal cell carcinoma metastasis to the brain: long-term outcomes and prognostic factors influencing survival and local tumor control. J Neurosurg. 2003. 98:342–349.
7. Singh K, Samartzis D, Vaccaro AR, Andersson GBJ, An HS, Heller JG. Current concepts in the management of metastatic spinal disease: The role of minimally-invaisve approaches. J Bone Joint Surg Br. 2006. 88:434–442.
8. Sohn MJ, Lee DJ, Lee HR, Hwang YJ, Ryoo JY, Jeon SR, Lee HY, Lee SH, Whang CJ. The application of stereotactic spinal radiosurgery for spinal tumors using Novalis shaped beam radiosurgical unit. J of the Kor Soc of Ster and Func Neurosurg. 2006. 2:68–74.
9. Takacs I, Hamilton AJ. Dickman CA, Fehlings MG, Gokaslan ZL, editors. Spinal stereotactic radiosurgey. Spinal cord and spinal column tumors: principles and practice. 2006. New York: Thieme;230–242.
10. Murphy MJ, Cox RS. The accuracy of dose localization for an image-guided frameless Radiosurgery system. Med Phys. 1996. 23:2043–2049.
11. Yu C, Main W, Taylor D, Kuduvalli G, Apuzzo MLJ, Adler JR, Wang MY. An anthropomorphic phantom study of the accuracy of Cyberknife spinal radosurgery. Neurosurgery. 2004. 55:1138–1149.
12. Yin FF, Ryu S, Ajlouni M, Yan H, Jin JY, Lee SW, Kim JK, Rock J, Rosenblum M, Kim JH. Image-gudied procedures for intensity-modulated spinal radiosurgery. J Neurosurg. 2004. 101:419–424.
13. Adler JR, Colombo F, Heibrum MP, Winston K. Toward an expanded view of radisurgey. Neurosurgey. 2004. 55:1374–1376.
14. Gabriel EM, Nashold BS. History of spinal cord stereotaxy. J Neurosurg. 1996. 85:725–731.
15. Nolte LP, Zmorano LJ, Jian Z, Whang Q, Lanqlotz F, Berlemann U. Image-guided insertion of transpedicular screws. Spine. 1995. 20:497–500.
16. Hamilton AJ, Lulu BA, Fosmir H, Stea B, Cassady JR. Preliminary clinical experience with linear accelerator-based spinal stereotactic Radiosurgery Technique and application. Neurosurgery. 1995. 36:311–319.
17. Hamilton AJ, Lulu BA, Fosmir H, Stea B, Cassady JR. LINAC-based spinal stereotactic Radiosurgery. Stereotactic Funct Neurosurg. 1996. 66:1–9.
18. Finn MA, Vrionis FD, Schmidt MH. Spinal Radiosurgery for metastatic disease of the spine. Cancer control. 2007. 14:405–411.
19. Rock JP, Ryu S, Yin FF. Novalis rdiosurgery for metastatic spine tumors. Neurosurg Clin N Am. 2004. 15:503–509.
20. Gerszten PC, Germanwala A, Burton SA, Welch WC, Ozhasoglu C, Vogel WJ. Stereotactic radiosurgery for spinal metastases from renal cell carcinoma. J Neurosurg Spine. 2005. 3:288–295.
21. Gerszten PC, Burton SA, Ozhasoglu C, Welch WC. Radiosurgery for spinal metastases. Spine. 2007. 32:193–199.
22. Lundsford LD, Kondziolka D, Flickinger JC. Kondziolka D, editor. Acoustic neuroma management: Evolution and revolution. Radiosurgery. 1998. vol 2. Basel: Karger;1–7.
23. Konziolka D, Levy EI, Niranjan A, Flickinger JC, Lunsford LD. Long-term outcomes after meningioma Radiosurgery: Physiscian and patient perspectives. J Neurosurg. 1999. 91:44–50.
24. Dodd RL, Ryu MR, Kamnerdsupaphon P, Gibbs IC, Chang SD, Adler JR. Cyberknife Radiosurgery for benign intradural extramedullary spinal tumors. Neurosurgery. 2006. 58:674–685.
25. Sinclair J, Chang SD, Gibbs IC, Adler JR. Multisession Cyberknife Radiosurgery for intramedullary spinal cord arteriovenous malformations. Neurosurgery. 2006. 58:1081–1089.
XML Download