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Lee, Kim, Kim, Kim, and Chong: Frequency of Mycoplasma pneumoniae Antibodies in Children Living on Jeju Island
Original Article
Korean Journal of Clinical Microbiology

Korean Journal of Clinical Microbiology 2012; 15(1): 32-36.

Published online: 20 March 2012

DOI: https://doi.org/10.5145/KJCM.2012.15.1.32

Frequency of Mycoplasma pneumoniae Antibodies in Children Living on Jeju Island

Kyutaeg Lee1, Woo Jin Kim1, Dong Lyul Kim1, Jae Hyang Kim1, Moo Sang Chong2

1Department of Laboratory Medicine, Cheju Halla General Hospital, Jeju-do, Korea.

2Department of Clinical Pathology, Cheju Halla College, Jeju-do, Korea.

Correspondence: Kyutaeg Lee, Department of Laboratory Medicine, Cheju Halla General Hospital, 1963-2, Yeon-dong, Jeju-si, Jeju-do 690-818, Korea. (Tel) 82-64-740-5256, (Fax) 82-64-740-5657, cornerstone@paran.com

Received 22 July 2011       Revised 2 December 2011       Accepted 15 December 2011

Copyright © 2012 The Korean Society of Clinical Microbiology

Abstract

Background

Mycoplasma pneumoniae (MP) is a major cause of community-acquired pneumonia in children. Currently, no study exists regarding the frequency of the mycoplasmal antibody on Jeju Island. The aim of the present study was to investigate the frequency of mycoplasmal antibody among children living on Jeju Island.

Methods

From March 2009 to February 2011, the frequency of mycoplasmal antibody among 1580 pediatric (<10 years old) patients who were tested for the mycoplasmal antibody titer in Cheju Halla Hospital were retrospectively investigated. The authors also analyzed the positive rates according to age, sex, and season.

Results

The frequency of mycoplasmal antibody titers were 69.4% for an antibody titer >1:40, 20.8% in an antibody titer >1:320, and 10.7% in an antibody titer >1:640. The positive rates of each antibody titer were lowest in children under the age of 6 months, and the positive rates increased gradually with age until 4 years, where the frequency showed a "plateau." There were minor cyclic increases of positive rate (>1:320, >1:640) every three months from August 2009 to June 2010, and there was a major increase of positive rate (>1:320, >1:640) from July 2010 to January 2011. However, there was no positive rate cyclic pattern of mycoplasmal antibody in the lower titer (>1:40) patients.

Conclusion

The frequency of mycoplasmal antibody titer is lowest under the age of 6 months. The positive rates rise gradually with age until the age of 4 years. The present study showed minor peaks of mycoplasmal antibody titer every three months and a major peak of mycoplasmal antibody titer. The results can be helpful for the interpretation and diagnosis of MP among pediatric patients on Jeju Island.

Keywords: Mycoplasma pneumoniae, Antibody titer, Jeju

Figures and Tables

Fig. 1
The positive rates of Mycoplasma pnuemoniae antibody titers by ages.
kjcm-15-32-g001
Fig. 2
The positive rates of Mycoplasma pnuemoniae antibody titers by time.
kjcm-15-32-g002
Table 1
Characteristics of patients by ages
kjcm-15-32-i001
Table 2
The positive rates (%) of Mycoplasma pnuemoniae antibody titers by ages
kjcm-15-32-i002
Table 3
The positive rates (%) of Mycoplasma pnuemoniae antibody titers by time
kjcm-15-32-i003

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