PDF
ePub
Citation
Print
Abstract
Mycoplasma hominis is a commensal organism in the genitourinary tract. Extragenital infections by M. hominis are rare, and its occurrence is usually limited to immunocompromised patients. Here we report two patients with extragenital infection by M. hominis. The first patient, a woman with angioimmunoblastic T cell lymphoma, underwent autologous peripheral blood stem cell transplantation. The second patient, a woman with endometrial cancer, received laparoscopically-assisted vaginal hysterectomy. They both presented with septic symptoms, including fever, and M. hominis was isolated from pleural effusion and ascitic fluid, respectively. We are reporting these two cases of extragenital infection by M. hominis with a literature review to emphasize that the rapid isolation of M. hominis with early treatment can lead to a better prognosis.
REFERENCES
1. Duffy LB, Crabb D, Searcey K, Kempf MC. Comparative potency of gemifloxacin, new quinolones, macrolides, tetracycline and clindamycin against Mycoplasma spp. J Antimicrob Chemother. 2000; 45(Suppl 1):29–33.
2. Yamaguchi M, Kikuchi A, Ohkusu K, Akashi M, Sasahara J, Takakuwa K, et al. Abscess formation due to Mycoplasma hominis infection after cesarean section. J Obstet Gynaecol Res. 2009; 35:593–6.
3. Lyon GM, Alspaugh JA, Meredith FT, Harrell LJ, Tapson V, Davis RD, et al. Mycoplasma hominis pneumonia complicating bilateral lung transplantation: case report and review of the literature. Chest. 1997; 112:1428–32.
4. Miranda C, Camacho E, Reina G, Turiño J, Rodríguez-Granger J, Yeste R, et al. Isolation of Mycoplasma hominis from extragenital cultures. Eur J Clin Microbiol Infect Dis. 2005; 24:334–7.
5. García C, Ugalde E, Monteagudo I, Saez A, Agüero J, Martinez-Martinez L, et al. Isolation of Mycoplasma hominis in critically ill patients with pulmonary infections: clinical and microbiological analysis in an intensive care unit. Intensive Care Med. 2007; 33:143–7.
6. Lee JH, Lee JH, Lee NY, Ha CW, Chung DR, Peck KR. Two cases of septic arthritis by Mycoplasma hominis after total knee replacement arthroplasty. Korean J Lab Med. 2009; 29:135–9.
7. Rohner P, Schnyder I, Ninet B, Schrenzel J, Lew D, Ramla T, et al. Severe Mycoplasma hominis infections in two renal transplant patients. Eur J Clin Microbiol Infect Dis. 2004; 23:203–4.
8. Kane JR, Shenep JL, Krance RA, Hurwitz CA. Diffuse alveolar hemorrhage associated with Mycoplasma hominis respiratory tract infection in a bone marrow transplant recipient. Chest. 1994; 105:1891–2.
9. Camara B, Mouzin M, Ribes D, Esposito L, Guitard J, Game X, et al. Perihepatitis and perinephric abscess due to Mycoplasma hominis in a kidney transplant patient. Exp Clin Transplant. 2007; 5:708–9.
10. Mufson MA. Mycoplasma hominis: a review of its role as a respiratory tract pathogen of humans. Sex Transm Dis. 1983; 10(4 Suppl):335–40.
11. Diekman MJ, Kuijper EJ, Boeschoten EW. Isolation of Mycoplasma hominis from peritoneal effluent of a CAPD patient. Perit Dial Int. 1991; 11:84–5.
12. Pile JC. Evaluating postoperative fever: a focused approach. Cleve Clin J Med. 2006; 73(Suppl 1):62–6.
13. Park HR, Kim YH, Lee HJ, Oh JS, Kim HJ. Usefulness of the mycofast test (MYCOFAST(R) Evolution 2) for the diagnosis of nongonococcal genitourinary infections. Korean J Urol. 2006; 47:1117–23.
XML Download