Journal List > Korean J Clin Microbiol > v.13(3) > 1038194

Korean J Clin Microbiol. 2010 Sep;13(3):135-139. Korean.
Published online September 30, 2010.  https://doi.org/10.5145/KJCM.2010.13.3.135
Copyright © 2010 The Korean Society of Clinical Microbiology
Fungemia due to Exophiala dermatitidis
Eun Sun Jeong, Jong Hee Shin, Myung Geun Shin, Soon Pal Suh and Dong Wook Ryang
Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea.

Correspondence: Jong Hee Shin, Department of Laboratory Medicine, Chonnam National University Medical School, 671 Jebong-ro, Dong-gu, Gwangju 501-757, Korea. (Tel) 82-62-220-5342, (Fax) 82-62-224-2518, Email: shinjh@chonnam.ac.kr
Received January 12, 2010; Revised July 13, 2010; Accepted August 20, 2010.

Abstract

We report a rare case of fungemia due to Exophiala (Wangiella) dermatitidis in a 4-month-old female infant who was admitted to an intensive care unit with sudden infant death syndrome (SIDS). E. dermatitidiswas repeatedly isolated from blood cultures (on the 28th and 32nd day of hospitalization) of the patient, who died on the 44th day of hospitalization. The fungus was identified by its morphological characteristics and DNA sequencing of both the D1/D2 domain and the ITS region of rDNA. To our knowledge, this is the first reported case of E. dermatitidis fungemia in Korea.

Keywords: Exophiala (Wangiella) dermatitidis; Fungemia; ITS; Sequencing

Figures


Fig. 1
Two weeks after incubation at 30℃ on the potato dextrose agar, the colonies appeared as black, reverse black, wet, and mucoid.
Click for larger image


Fig. 2
Microscopically, septate, and pale olivaceous hyphae and black yeast synanarmorphs were found. Conidiogenous cells were cylindrical, with rounded apeces producing one-celled conidia. Round to ovoid, pale brown conidia accumulated in balls or slipped down the side of conidiophores (Lactophenol cotton blue stain, ×400).
Click for larger image


Fig. 3
A pyelogenetic tree of Exophiala and neighboring species, constructed by using neighbor-joining algorithm.
Click for larger image

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