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Park, Uh, Lee, Jang, Yoon, and Namgoong: A Case of Bacteremia Caused by Rothia dentocariosa
Original Article

Korean J Clin Microbiol 2009;12(3):133-137.

Published online: 22 September 2009

DOI: https://doi.org/10.5145/KJCM.2009.12.3.133

A Case of Bacteremia Caused by Rothia dentocariosa

Soon Deok Park1, Young Uh1, Hyeun Gyeo Lee1, Ih Ho Jang1, Kap Jun Yoon1, Mee Kyung Namgoong2

1Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea

2Department of Pediatrics, Yonsei University Wonju College of Medicine, Wonju, Korea

Correspondence: Young Uh, Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, 162, Ilsan-dong, Wonju 220-701, Korea. (Tel) 82-33-741-1592, (Fax) 82-33-731-0506, (E-mail) u931018@yonsei.ac.kr

Received 26 March 20091 May 2009       Accepted 15 July 2009

Copyright © 2009 Korean Journal of Clinical Microbiology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Rothia dentocariosa, a pleomorphic gram-positive branching bacillus, is a common inhabitant of the nose and throat. It is a well-known causative agent of dental plaques and periodontal diseases. Although generally regarded as having a low virulence to humans, R. dentocariosa has been recognized as causative agents of in-fective endocarditis and bacteremia with increasing frequency. Consequently, it can be a very serious pathogen when isolated from usually sterile sites such as blood or cerebrospinal fluid. We report a case of Rothia dentocariosa bacteremia without endocarditis in a 17-month-old male patient with fever, vomiting and diarrhea.

Keywords: Bacteremia, Rothia dentocariosa, Blood culture

REFERENCES

1. Onishi M. Study of the Actinomyces isolated from the deeper layer of carious dentine. Shikagaku Zasshi. 1949; 6:273–82.
2. Georg LK, Brown JM. Rothia gen nov, an aerobic genus of the family Actinomycetaceae. Int J Syst Bacteriol. 1967; 17:79–88.
3. von Graevenitz A. Rothia dentocariosa: taxonomy and differential diagnosis. Clin Microbiol Infect. 2004; 10:399–402.
4. Tanner ACR, Haffer C, Bratthall GT, Visconti RA, Socransky SS. A study of the bacteria associated with advancing periodontitis in man. J Clin Periodontol. 1979; 6:278–307.
crossref
5. Lesher RJ, Gerencser VF, Morrison DJ. Presence of Rothia dentocariosa strain 477 serotype 2 in gingiva of patients with inflammatory periodontal disease. J Dent Res. 1977; 56:189.
6. Lutwick LI, Rockhill RC. Abscess associated with Rothia dentocariosa. J Clin Microbiol. 1978; 8:612–3.
7. Scharfen J. Untraditional glucose fermenting actinomycetes as human pathogens-Part II: Rothia dentocariosa as a cause of abdominal actinomycosis and a pathogen for mice. Zentralbl Bakteriol [Orig A]. 1975; 233:80–92.
8. Llopis F, Carratala J. Vertebral osteomyelitis complicating Rothia dentocariosa endocarditis. Eur J Clin Microbiol Infect Dis. 2000; 19:562–3.
9. Wallet F, Perez T, Roussel-Delvallez M, Wallaert B, Courcol R. Rothia dentocariosa: two new cases of pneumonia revealing lung cancer. Scand J Infect Dis. 1997; 29:419–20.
10. Bibashi E, Kokolina E, Mitsopoulos E, Kontopoulou K, Sofianou D. Peritonitis due to Rothia dentocariosa in a patient receiving continuous ambulatory peritoneal dialysis. Clin Infect Dis. 1999; 28:696.
11. Ergin C, Sezer MT, Agalar C, Katirci S, Demirdal T, Yayli G. A case of peritonitis due to Rothia dentocariosa in a CAPD patient. Perit Dial Int. 2000; 20:242–3.
12. Isaacson JH, Grenko RT. Rothia dentocariosa endocarditis complicated by brain abscess. Am J Med. 1988; 84:352–4.
13. Binder D, Zbinden R, Widmer U, Opravil M, Krause M. Native and prosthetic valve endocarditis caused by Rothia dentocariosa: diagnostic and therapeutic considerations. Infection. 1997; 25:22–6.
14. Ferraz V, McCarthy K, Smith D, Koornhof HJ. Rothia dentocariosa endocarditis and aortic root abscess. J Infect. 1998; 37:292–5.
15. Shin JH, Shim JD, Kim HR, Sinn JB, Kook JK, Lee JN. Rothia dentocariosa septicemia without endocarditis in a neonatal infant with meconium aspiration syndrome. J Clin Microbiol. 2004; 43:4891–2.
16. Karlsson MD, Jacobsson B. Intrauterine fetal death associated with Rothia dentocariosa: a case report. Am J Obstet Gynecol. 2007; 197:e6–7.
17. Funke G, Bernard KA. Coryneform Gram-positive Rods. Murray PR, editor. eds.Manual of Clinical Microbiology. 9th ed.Washington D.C.: American Society for Microbiology;2007. p. 485–514.
crossref
18. Brown JM, Georg LK, Waters LC. Laboratory identification of Rothia dentocariosa and its occurrence in human clinical materials. Appl Microbiol. 1969; 17:150–6.
19. Lesher RJ, Gerencser MA, Gerencser VF. Morphological, biochemical, and serological characterization of Rothia dentocariosa. Int J Syst Bacteriol. 1974; 24:154–9.
20. Bernard KA, Bellefeuille M, Hollis DG, Daneshvar MI, Moss CW. Cellular fatty acid composition and phenotypic and cultural characterization of CDC fermentative coryneform groups 3 and 5. J Clin Microbiol. 1994; 32:1217–22.
crossref
21. Funke G, von Graevenitz A, Clarridge JE, Bernard KA. Clinical microbiology of coryneform bacteria. Clin Microbiol Rev. 1997; 10:125–59.
crossref
22. Madianos PN, Lieff S, Murtha AP, Boggess KA, Auten RL Jr, Beck JD, et al. Maternal periodontitis and prematurity. Part II: Maternal infection and fetal exposure. Ann Periodontol. 2001; 6:175–82.
crossref
23. Boudewijns M, Magerman K, Verhaegen J, Debrock G, Peetermans WE, Donkersloot P, et al. Rothia dentocariosa, endocarditis and mycotic aneurysms: case report and review of the literature. Clin Microbiol Infect. 2003; 9:222–9.

Fig. 1.
Gram stain morphologies of Rothia dentocariosa showing pleomorphic gram-positive branching bacilli.
kjcm-12-133f1.tif
Fig. 2.
Rothia dentocariosa colonies grown for 24 hours on blood agar plate. Note white, smooth colonies with a diameter of approximately 1 mm.
kjcm-12-133f2.tif
Table 1.
Comparison of 16S rRNA sequence between our strain and AY594189.1∗
kjcm-12-133t1.tif
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