A Fatal Case of Infective Endocarditis Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus ST72 in Korea

Seong-Ho Choi; Jin-Won Chung

doi:10.5145/kjcm.2008.11.2.129

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Choi and Chung: A Fatal Case of Infective Endocarditis Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus ST72 in Korea

Original Article

Korean J Clin Microbiol 2008;11(2):129-131.

Published online: 20 October 2008

DOI: https://doi.org/10.5145/kjcm.2008.11.2.129

A Fatal Case of Infective Endocarditis Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus ST72 in Korea

Seong-Ho Choi, Jin-Won Chung

Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea

Correspondence: Jin-Won Chung, Department of Internal Medicine, Chung-Ang University Medical Center, 224-1, Heukseok-dong, Dongjak-gu, Seoul 156-755, Korea. (Tel) 82-2-6299-1420, (Fax) 82-2-825-7571, (E-mail) drjwchung@cau.ac.kr

Received 8 September 2008 Accepted 25 September 2008

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The advent of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been a worldwide threat to public health for the past decade. We report a fatal case of infective endocarditis caused by a non-USA300, Panton-Valentine leukocidin toxin-negative CA-MRSA clone. This is a serious case of CA-MRSA infection caused by a se-quence type (ST) 72 clone, which is one of the common CA-MRSA clones circulating in Korea where se-rious CA-MRSA infections have been rare.

Keywords: Staphylococcus aureus, Endocarditis, Methicillin Resistant

References

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Fig. 1.

Molecular detection of type IV SCCmec and PVL virulence gene. PCR amplification with specific primers shows the presence of mecA and type IV SCCmec in the CA-MRSA isolate. However, PCR for detection of the PVL gene shows the absence of PVL gene in the isolate.

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