Anti-osteoporotic Drugs and Fracture Healing Mechanism

Kyu Hyun Yang

doi:10.12671/jkfs.2011.24.2.212

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Yang: Anti-osteoporotic Drugs and Fracture Healing Mechanism

Review Article from Symposium

Journal of the Korean Fracture Society

Journal of the Korean Fracture Society 2011; 24(2): 212-216.

Published online: 13 April 2011

DOI: https://doi.org/10.12671/jkfs.2011.24.2.212

Anti-osteoporotic Drugs and Fracture Healing Mechanism

Kyu Hyun Yang, M.D.

Department of Orthopaedic Surgery, Gangnam Severance Hospital, Seoul, Korea.

Address reprint requests to: Kyu Hyun Yang, M.D. Department of Orthopaedic Surgery, Gangnam Severance Hospital, 146-92, Dokok-dong, Gangnam-gu, Seoul 135-720, Korea. Tel: 82-2-2019-3414, Fax: 82-2-573-5393, kyang@yuhs.ac

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Figures and Tables

Fig. 1

Molecular mechanism of action of bisphosphonate.

Fig. 2

Alendronate increases the callus size compared to control (OVX-ovariectomy), EE2 (estrogen) and RLX (raloxifen).

Fig. 3

Structure of multicellular remodelling units.

Fig. 4

Bisphophonate rescue regimen in case of delayed bone formation after osteotomy and distraction.

Fig. 5

Zoledronate enhances bone in-growth in porous implant.

Fig. 6

Teriparatide (1-34 PTH) injection shortened the healing time of Colles' fracture.

Fig. 7

PTH enhances bone growth around the screw and increases pull-out strength significantly compared to control.

References

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