Depressive Symptom-Related Factors in Patients with Breast Cancer

Eun Young Park; Young Tae Bae; Jee Yeon Lee; Hyung-Il Seo; Eun Soo Moon; Youn Joo Jung

doi:10.4048/jbc.2011.14.S.S64

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Park, Bae, Lee, Seo, Moon, and Jung: Depressive Symptom-Related Factors in Patients with Breast Cancer

Original Article

Journal of Breast Cancer

Journal of Breast Cancer 2011; 14(Suppl 1): S64-S69.

Published online: 28 February 2011

DOI: https://doi.org/10.4048/jbc.2011.14.S.S64

Depressive Symptom-Related Factors in Patients with Breast Cancer

Eun Young Park, Young Tae Bae, Jee Yeon Lee, Hyung-Il Seo, Eun Soo Moon¹, Youn Joo Jung²

Department of Surgery, Postgraduate College of Medicine, Pusan National University, Busan, Korea.

¹Department of Psychiatry, Postgraduate College of Medicine, Pusan National University, Busan, Korea.

²Breast Cancer Center, Postgraduate College of Medicine, Pusan National University, Busan, Korea.

Correspondence: bytae@pusan.ac.kr

Received 2 September 2010 Accepted 12 January 2011

Abstract

Purpose

Patients with breast cancer are at risk for developing psychological distress and psychiatric disorders such as depression. The aim of this study was to assess the depressive symptom related factors in women with breast cancer.

Methods

A total of 211 patients with breast cancer who had undergone an operation within 5 years participated in this survey with consent. Depressive symptoms in patients were measured using the 21-item Beck Depression Inventory (BDI) questionnaire in the outpatient clinic and sociodemographic, clinicopathologic factors of the patients were analyzed with a BDI score. The patients were divided into group A (BDI<16, n=146) and group B (BDI≥16, n=65).

Results

The mean age of the patients was 49.2 years and the mean follow-up period was 22 months. In the univariate analyses, postmenopausal status (p=0.014), tumor size (p=0.023) and presence of progesterone receptor (p=0.012) were significantly associated with depressive symptom. In multivariate analysis, only postmenopause (p=0.021) and tumor size (p=0.018) were related with depressive symptom.

Conclusion

Depressive symptom is common in patients with breast cancer and a screening test for depression is needed in breast cancer patient who experienced menopause or has bigger tumor size.

Keywords: Breast neoplasms, Depressive symptom, Postmenopause, Tumor size

Figures and Tables

Table 1

Sociodemographic factors associated with depressive symptom in breast cancer patients

^*Not depressed group; ^†Depressed group; ^‡Logistic regression model; ^§Mean (range).

Table 2

Clinicopathologic factors associated with depressive symptom in breast cancer patients

^*Not depressed group; ^†Depressed group; ^‡Logistic regression model; ^§Mean (range).

Table 3

Multivariate analysis for factors associated with depressive symptom in patients with breast cancer

OR=odds ratio; CI=confidence interval.

^*Multivariate logistic regression model.

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