Biopsychosocial Predictors of the Quality of Life in Breast Cancer Patients

Eun Hye Ha; Sun Hee Lee; Joon Jeong; Hy De Lee; Jeong Eon Lee; Seok Jin Nam; Jung Hyun Yang

doi:10.4048/jbc.2010.13.2.219

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Ha, Lee, Jeong, Lee, Lee, Nam, and Yang: Biopsychosocial Predictors of the Quality of Life in Breast Cancer Patients

Original Article

Journal of Breast Cancer

Journal of Breast Cancer 2010; 13(2): 219-226.

Published online: 29 June 2010

DOI: https://doi.org/10.4048/jbc.2010.13.2.219

Biopsychosocial Predictors of the Quality of Life in Breast Cancer Patients

Eun Hye Ha, Sun Hee Lee, Joon Jeong¹

, Hy De Lee¹, Jeong Eon Lee², Seok Jin Nam², Jung Hyun Yang²

Department of Childwelfare & Child Studies, Sookmyung Women's University, Seoul, Korea.

¹Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

²Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Corresponding author (graceha@sookmyung.ac.kr)

Received 30 November 2009 Accepted 16 February 2010

Abstract

Purpose

The purpose of this study was to identify biopsychosocial predictors of the quality of life in breast cancer patients. Disease factors (disease stage, type of surgery, type of treatment, family history), personal factors (age, education level, income), and psychosocial factors (psychological symptoms, optimism, self-esteem, husband's support, cancer coping) were included in biopsychosocial predictors.

Methods

A total of 128 breast cancer patients were recruited. Subjects were assessed by the Optimism Scale, the Selfesteem Scale, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Breast Cancer Module (EORTC QLQ-BR23), the Symptom Checklist-90-Revision (SCL-90-R), and the Korean Cancer Coping Questionnaire (KCCQ).

Results

Disease factors and personal factors were not different between the high and low quality of life group. But the psychosocial factors were significantly different. Somatization, anxiety, depression, interpersonal sensitivity, hostility, and phobic anxiety showed significantly lower scores in the high quality of life group than the low group. Optimism, self-esteem and husband's support showed significantly higher score in the high quality of life group than the low group. In a stepwise multiple regression analysis, not disease factors and personal factors but the psychosocial factors significantly predicted the quality of life in breast cancer patients. Especially, somatization and depression significantly predicted the quality of life.

Conclusion

Among psychosocial factors, somatization and depression were the most significant predictors of the quality of life in breast cancer patients. These results supported psychosocial intervention should be needed to breast cancer patients, in order to improve the quality of life.

Keywords: Breast neoplasms, Depression, Quality of life, Somatoform disorders

Figures and Tables

Table 1

Demographic and clinical characteristics of the subjects (n=128)

Table 2

Mean scores of quality of life and psychosocial factors (n=128)

SD=standard deviation; Min=minimum; Max=maximum; SCL-90-R=Symptom Checklist-90-Revision; KCCQ=Korean Cancer Coping Questionnaire; EORTC QLQ-BR23=The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Breast Cancer Module.

Table 3

Pearson correlations of variables (n=128)

1-①=Somatization; 1-②=Anxiety; 1-③=Depression; 1-④=Interpersonal sensitivity; 1-⑤=Hostility; 1-⑥=Phobic anxiety; 2=Optimism; 3=Self-esteem; 4=Husband's support; 5-①=KCCQ Interpersonal; 5-②=KCCQ Personal total; 6-①=EORTC QLQ-BR23 Symptom scales; 6-②=EORTC QLQ-BR23 Functional scales; 6-③=EORTC QLQ-BR23 Total; KCCQ=Korean Cancer Coping Questionnaire; EORTC QLQ-BR23=The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Breast Cancer Module.

Table 4

Comparisons between high group and low group in the quality of life (n=64)

SCL-90-R=Symptom Checklist-90-Revision; KCCQ=Korean Cancer Coping Questionnaire.

^*χ²; ^†Mean±standard deviation.

Table 5

Predictors of the quality of life (n=128)

SCL-90-R=Symptom Checklist-90-Revision; KCCQ=Korean Cancer Coping Questionnaire.

^*Dummy code; Every first line was a criterion value, so the value was not describe here; ^†Stage I R²=0.045, F=0.961, p=0.455; ^‡Stage II R²=0.096, F=1.124, p=0.349, ΔR²=0.051, ΔF=1.306, Δp=0.266; ^§Stage III R²=0.521, F=5.196, p=0.000, ΔR²=0.425, ΔF=8.471, Δp=0.000.

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ORCID iDs: Joon Jeong
https://orcid.org/http://orcid.org/0000-0003-0397-0005
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