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Abstract
Malignant fibrous histiocytoma is the most common form of soft tissue sarcoma during middle and late adulthood in the deep connective tissues of the extremities, abdominal cavity, and retroperitoneum. Primary breast sarcoma is a rare disease entity, comprising less than 1% of all breast malignancies. Malignant fibrous histiocytoma of the breast is very rare. We presented one case of a malignant fibrous histiocytoma of the right breast in a 49-year-old woman and report the case with a review of the literature.
Figures and Tables
 | Fig 1The ultrasonographic findings of malignant fibrous histiocytoma. Several large hypoechoic & isoechoic masses are noted in lower half of right breast and part of them are located in subcutaneous layer (A) and lymph nodes in right axilla are enlarged (B). These findings are included in BI-RADS category 5.
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 | Fig 2Histopathologic findings of malignant fibrous histiocytoma (A & B; ×40 & ×100, HE stain) Highly pleomorphic spindle shaped cells are observed in cellular tumor tissue. The tumor shows broad myxoid tissue (arrow) abutting cellular area (A) and fascicular pattern of pleomorphic spindle shaped cells (B).
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 | Fig 3PET-CT findings. Intense F-18 FDG accumulation (arrow) in subareolar and lower lateral portion of right breast (A) and several focal FDG uptake (arrow) in right axilla (B) are observed.
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