The Role and Significance of Preoperative Breast MRI in the Setting of Breast Cancer

Jun Woo Jin; Cha Kyong Yom; Min Young Koo; Byung In Moon; Kook Jin Choi; Hye Young Choi

doi:10.4048/jbc.2008.11.3.146

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Jin, Yom, Koo, Moon, Choi, and Choi: The Role and Significance of Preoperative Breast MRI in the Setting of Breast Cancer

Original Article

Journal of Breast Cancer

Journal of Breast Cancer 2008; 11(3): 146-150.

Published online: 30 September 2008

DOI: https://doi.org/10.4048/jbc.2008.11.3.146

The Role and Significance of Preoperative Breast MRI in the Setting of Breast Cancer

Jun Woo Jin, Cha Kyong Yom², Min Young Koo, Byung In Moon, Kook Jin Choi, Hye Young Choi¹

Department of General Surgery, School of Medicine, Ewha Womans University, Seoul, Korea.

¹Department of Radiolology, School of Medicine, Ewha Womans University, Seoul, Korea.

²Department of General Surgery, Kangbuk Samsung Hospital, Seoul, Korea.

mbit@ewha.ac.kr

Received 7 July 2008 Accepted 12 September 2008

Abstract

Purpose

Accurate preoperative assessment of breast cancer is important to determine the extent of disease and the plan for surgery. The purpose of this study was to evaluate the efficacy of preoperative breast magnetic resonance imaging (MRI) in breast cancer patients.

Methods

Between January 2001 and October 2007, 457 consecutive patients who had undergone surgical treatment for breast cancer were retrospectively studied. We compared 303 patients from the non-preoperative MRI group (group A) to 154 patients from the preoperative MRI group (group B). The impact of preoperative MRI was evaluated for each patient with regard to changes in therapeutic intervention.

Results

MRI alone revealed 17 new lesions. The results of the MRI led to a change in 9.1% of the planned surgical procedures. Tumor size was more accurately defined in patients undergoing MRI than in those undergoing ultrasound imaging.

Conclusion

Breast MRI could be recommended as a preoperative diagnostic procedure in patients allocated to receive breast conservation surgery, because MRI may reveal unsuspected multifocal or multicentric tumors or carcinoma infiltrations and may result in changes in therapy.

Keywords: Magnetic resonance imaging, Breast cancer, Surgery, Size

Figures and Tables

Fig 1

Seventeen new lesions diagnosed by MRI have been managed as follows.

MRM=modified radical mastectomy; BCS=breast conserving surgery.

^*The figures in parentheses mean the number of cases.

Fig 2

Regression graph shows the predicted tumor size by sonography and MRI versus histological size. Tumor size was more accurately defined in MRI (R²=0.589) than sonography (R²=0.411).

Table 1

Clinical characteristics of patients

Group A=patients without preoperative MRI; Group B=patients with preoperative MRI; G1=well differentiated; G2=moderated differentiated; G3=undifferentiated; ER=estrogen receptor; PR=progesterone receptor; Triple test, positive=ER(+) or PR(+) or HER2/neu(+), negative=ER(-) and PR(-) and HER2/neu(-).

Table 2

Operation methods and recurrence rate

Group A=patients without preoperative MRI; Group B=patients with preoperative MRI; MRM=modified radical mastectomy; BCS=breast conserving surgery.

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