Clinicopathologic Features of the Papillary Breast Lesions Diagnosed on Ultrasonography-guided Core Needle Biopsy

Jung Hyun Park; Ja Seong Bae; Young Jin Suh; Woo Chan Park; Byung Joo Song; Jeong Soo Kim; Sang Seol Jung

doi:10.4048/jbc.2007.10.4.269

Journal List > J Breast Cancer > v.10(4) > 1036082

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Park, Bae, Suh, Park, Song, Kim, and Jung: Clinicopathologic Features of the Papillary Breast Lesions Diagnosed on Ultrasonography-guided Core Needle Biopsy

Original Article

Journal of Breast Cancer

Journal of Breast Cancer 2007; 10(4): 269-272.

Published online: 31 December 2007

DOI: https://doi.org/10.4048/jbc.2007.10.4.269

Clinicopathologic Features of the Papillary Breast Lesions Diagnosed on Ultrasonography-guided Core Needle Biopsy

Jung Hyun Park, Ja Seong Bae, Young Jin Suh, Woo Chan Park, Byung Joo Song, Jeong Soo Kim, Sang Seol Jung

Department of Surgery, The Catholic University of Korea, Seoul, Korea.

bjsong@catholic.ac.kr

Received 8 October 2007 Accepted 29 November 2007

Abstract

Purpose

It is well recognized that distinguishing benign papillary lesions from malignant papillary lesions on core needle biopsy may pose difficult diagnostic problems. This study was conducted to define the potential role of ltrasoundguided core biopsy for the diagnosis of papillary lesions of the breast.

Methods

Twelve hundred and seventy nine women consecutively underwent 14-gauge core biopsy between January 2004 and December 2006. Of the 1,279 patients, 42 patients (3.2%) had papillary lesions of the breast on core needle biopsy. Of these 42 patients, 35 patients underwent surgical excision or sono-guided vacuum assisted excision. We compared the pathologic results of the excised specimens with the pathologic results on core needle biopsy.

Results

Of the 35 patients, 23 patients underwent surgical excision and 12 patients underwent sono-guided vacuum assisted excision. Three patients with intraductal papilloma without atypism on the core needle biopsy were confirmed to have intraductal papilloma accompanied with atypism by the final pathology. All 4 patients with papillomatosis or intraductal papilloma with atypism at core needle biopsy were confirmed to have intraductal papilloma with atypism by the final pathology. There were no patients identified to have breast cancer.

Conclusion

Our results revealed the accuracy of core needle biopsy for making the diagnosis of papillary lesions of the breast. Surgical excision may not always be necessary for papillary lesion of the breast that is diagnosed on core needle biopsy. Surgical excision is considered in patients with papillomatosis or papillary lesions with atypism seen on core needle biopsy.

Keywords: Papillary neoplasm, Core needle biopsy

Figures and Tables

Table 1

Clinical characteristics of patients with papillary neoplasm

Table 2

Symptoms associated with papillary neoplasm

FDH=florid ductal hyperplasia; ADH=atypical ductal hyperplasia.

Table 3

Ultrasonographic findings of papillary lesion

BIRADS=Breast imaging and reporting data system.

Table 4

Relation between results of CNB and final pathologic results

CNBx=core needle biopsy; FDH=florid ductal hyperplasia; ADH=atypical ductal hyperplasia.

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