Tumoral Calcinosis at Lumbar Region

Jae-Lim Cho; Chang-Nam Kang; Ye-Soo Park; Jin-Woo Choe

doi:10.4184/jkss.2007.14.3.207

Journal List > J Korean Soc Spine Surg > v.14(3) > 1035775

Go to TopGo to Top Go to BottomGo to Bottom

TOOLS

Cho, Kang, Park, and Choe: Tumoral Calcinosis at Lumbar Region

A Case Report

Journal of Korean Spine Surg 2007;14(3):207-211.

Published online: 21 February 2007

DOI: https://doi.org/10.4184/jkss.2007.14.3.207

Tumoral Calcinosis at Lumbar Region

Jae-Lim Cho, M.D., Chang-Nam Kang, M.D., Ye-Soo Park, M.D.^#, Jin-Woo Choe, M.D.

Department of Orthopaedic Surgery, Hanyang University College of Medicine, Seoul, Korea

^#Department of Orthopaedic Surgery, Guri Hospital, Hanyang University College of Medicine, Guri, Korea

Address reprint requests to Chang-Nam Kang, M.D. Department of Orthopaedic Surgery, College of Medicine, Hanyang University,#17 Haengdang-dong, Sungdong-gu, Seoul, Korea Tel: 82-2-2290-8483, Fax: 82-2-2299-3774, E-mail: cnkang65@hanyang.ac.kr

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Tumoral calcinosis is a rare disease involving the ectopic calcifications in the major juxtaarticular sites that was first described by Inclan Alberto in 1943. The etiology of tumoral calcinosis is still obscure. A disturbance of the phosphate metabolism in the kidney has been considered a major cause. However, some patients have no laboratory abnormalities. Tumoral calcinosis in the spine has not been reported in Korea. Recently, we encountered a case of tumoral calcinosis in the lumbar region. The clinical and pathological findings are discussed with a review of the relevant literature.

Keywords: Lumbar region, Tumoral calcinosis

REFERENCES

1). Inclan A, Leon P, Camezo MG. Tumoral calcinosis. J.A.M.A. 1943; 121:490–495.

2). Mitnick PD, Goldfarb S, Slatopolsky E, Lemann J Jr, Gray RW, Agus ZS. Calcium and phosphate metabolism in tumoral calcinosis. Ann Intern Med. 1980; 92:482–487.

3). Harkness JW, Perters HS. Tumoral calcinosis. A report 6 cases. J Bone and Joint Surg Am. 1967; 49:721–731.

4). Thomson JEM, Tanner FH. Tumoral calcinosis. J Bone and Joint Surg Am. 1949; 31:132–140.

5). Baldursson H, Evans EB, Dodge W, Jackson T. Tumoral calcinosis with hyperphosphatemia. J Bone and Joint Surg. 1969; 51A:960–964.

6). Lever WF, Schaumberg-Lever G. Histopathology of the skin. 6 ^th ed. Philadelphia: JB Lippincott Co;420. 1983.

7). Duret MH. Tumeurs multiples et singulieres des bourse sereuses. Bulletin de la Societe Anatomique de Paris. 1899; 74:725–731.

8). Teutschlaender O. Lipid calcinosis. Zieglers Beitr. 1947; 110:402–405.

9). Lafferty FW, Reynold ES, Peason OH. Tumoral calcinosis. Am J Med. 1965; 38:105–118.

10). Kirk TS, Simon MA. Tumoral calcinosis. Report of a case with successful medical management. J Bone and Joint Surg Am. 1981; 63:1167–1169.

11. Durant DM, Riley LH 3 rd, Burger PC, McCarthy EF. Tumoral calcinosis of the spine. A study of 21 cases. Spine. 2001; 26:1673–1679.

Fig. 1.

It is a clinical photograph at presentation.

Fig. 2.

Lateral X-ray of lumbar spine shows scanty calcification (arrow) at L3~4 interspinous ligament area.

Fig. 3.

Sagittal images of MRI shows a mass at interspinous ligament area. T1-weighted and T2-weighted images show that heterogenous low signal change is surrounded by a rim of increased signal. (A) T1-weighted image, (B) T2-weighted image.

Fig. 4.

Axial images of MRI shows septum of increased signal at T1-weighted and T2-weighted image. T1 weighted image shows sedimentation sign (arrow). (A) T1-weighted image, (B) T2-weighted image.

Fig. 5.

It is a photograph of the mass after excision. The excised specimen is measured 1.5×2.0×2.0 cm in size. (A) Axial view of the mass, (B) Sagittal view of the mass

Fig. 6.

The excised specimen is cutted. It is septated by dense fibrous septum, containing milk-like fluid and chalky materials.

Fig. 7.

It is a histologic findings (H-E staining). The section shows nodular aggregates of amorphous calcified mate-rial bordered by a proliferation of macrophages and multinucleated osteoclast like giant cells. The nodules are separated by bands of dense fibrous tissue.

TOOLS

Similar articles