Journal List > J Korean Soc Spine Surg > v.12(1) > 1035691

Kim, Kang, Park, Na, Kim, Ahn, Lee, and Choy: Availability of Intradiscal Injection of Marcaine as a Pain Relief Test for Diagnosis of Internal Disc Disruption

Abstract

Study Design

A retrospective study

Objectives

To investigate the availability of an intradiscal injection of marcaine as a pain relief test to enhance specificity in the diagnosis of IDD.

Summary of Literature Review

The diagnosis and treatment of IDD have been controversial. A discography, which has been widely used for the diagnosis of IDD, has many problems that might result in a faulty diagnosis.

Materials and Methods

Twenty nine patients, with an average age and duration of symptom of 36.9 years (22 to 46 years) and 5 years 1month (6 months to 10 years), respectively, were reviewed. A fter the discography, the marcaine was injected. Based on the responses after the injection, the group was sub- divided into a further two groups.
Group A (n=19): transient pain relief and surgical treatment was performed.
Group B (n=10): no pain relief and conservative treatment was performed. A n analysis to examine the correlation between the response to marcaine and age, duration of symptom, subjective pain level, number of disc degeneration and high intensity zone was also performed, and the clinical results quantified.

Results

The agreement rate between the discography and response to marcaine was 55.2%. The longer the symptom duration, the more meaningful were the responses to the marcaine injection (p<0.05). The result of surgical treatment was important statistically, as the pain was relieved from 8.6± 0.97 to 1.8± 0.42 points, and the ODI decreased from 68± 16.92 to 30± 9.97%(p<0.05).

Conclusions

A n intradiscal injection of marcaine, as the pain relief test, can enhance the specificity for the diagnosis of IDD.

REFERENCES

1). Guyer RD, Ohnmeiss DD. Lumbar discography: Position statement from the North American Spine Society Diagnostic and Therapeutic Committee. Spine. 1995; 20:2048–2059.
2). Lee CK, Vessa P, Lee JK. Chronic disabling low back pain syndrome caused by internal disc derangement. Spine. 1995; 20:356–361.
3). Lee CK, Langrana NA. Lumbosacral spinal fusion: A biomechanical study. Spine. 1984; 9:574–581.
crossref
4). Blumenthal SL, Baker J, Dossett A, Selby DK. The role of anterior lumbar fusion for internal disc disruption. Spine. 1988; 13:566–569.
crossref
5). Crock HV. A reappraisal of intervertebral disc lesions. Med. J. Aust. I. 1970. 983–989.
6). Nachemson A. Lumbar discography-where are we today? Spine. 1989; 14:555–557.
7). Schwarzer A, Bogduk N. Letter to Editor on “ The Preva -lence and Clinical features of internal Disk Disruption in patient with Low Back Pain.” Spine. 1996; 21:776.
8). Carragee EJ, Tanner CM, Yang B, et al. False positive findings on lumbar discography. Spine. 1999; 24:2542–2547.
9). Crock HV. Internal disc disruption: A challenge to disc prolapse fifty years on. Spine. 1988; 11:267–271.
10). Bogduk N, Tynan W, Wilson AS. The nerve supply to the human lumbar intervertebral discs. J Anat. 1981; 132:29–36.
11). Yoshizawa H, O’ Brien JP, Smith WT, et al. N eu -ropathology of intervertebral disc removed for low back pain. J Pathol. 1980; 132:95–104.
12). Weinstein J, Claverie W, Gibson S. The pain of discography. Spine. 1988; 13:1344–1348.
crossref
13). Saal JS. The role of inflammation in lumbar pain. Spine. 1995; 20:1821–1827.
crossref
14). Osti OL, Fraser RD. MRI and discography of annular tears and intervertebral disc degeneration. A prospective clinical comparison. J Bone Joint Surg. 1992; 74-B:431–435.
crossref
15). Birney TJ, White JJ Jr, Berens D, Kuhn G. Comparison of MRI and discography in the diagnosis of lumbar degenerative disc disease. J Spinal Disord. 1992; 5:417–423.
crossref
16). Gunzbury R, Parkinson R, Moore R, et al. A cadevaric study comparing discography, magnetic resonance imaging, histology, and mechanical behavior of the human lumbar disc. Spine. 1992; 17:417–426.
17). Holt EP. The question of lumbar discography. J Bone Joint Surg. 1968; 50:720–726.
crossref
18). Simmons EH, Segil CM. An evaluation of discography in the localization of symptomatic levels in discogenic dis -ense of the spine. Clin Orthop. 1975; 108:57–69.
19). Walsh TR, Weinstein JN, Spratt KF, Lehmann TR, Aprill C, Sayre H. Lumbar discography in normal subjects. J Bone Joint Surg. 1990; 72-A:1081–1088.
20). Gibson MJ, Buckley J, Mawhinney R, Mulholland RC, Worthington BS. Magnetic resonance imaging and discography in the diagnosis of disc degeneration. A comparative study of 50 disc. J Bone Joint Surg. 1986; 68-B:369–373.
21). Schneiderman G, Flannigan B, Kingston S, Thomas J, Dillin WH, Watkins RG. Magnetic resonance imaging in the diagnosis of disc degeneration: Correlation with discography. Spine. 1987; 12:276–281.
22). Parfenchuck TA, Janssen ME. A correlation of cervical magnetic resonance imaging and discography/computed tomographic discograms. Spine. 1994; 24:2819–2825.
crossref
23). Aprill C, Bogduk N. High-intensity zone: A diagnostic sign of painful lumbar disc on magnetic resonance imaging. The British Journal of Radiology. 1992; 65:361–369.
crossref
24). Ricketson R, Simmons JW, Hauser BO. The prolapsed intervertebral disc. The high-intensity zone with discography correlation. Spine. 1996; 221:2758–2762.
25). Schellhas KP, Pollei SR, Gundry CR, Heithoff KB. Lumbar disc high-intensity zone. Correlation of magnetic resonance imaging and discography. Spine. 1996; 21:79–86.
26). Smith SE, Darden BV, Rhyne AL, Wood KE. Outcome of unoperated discogram-positive low back pain. Spine. 1995; 15(20):1997–2000. discussion 2000-1.
crossref
27). Simmons JW, McMillin JN, Emery SF, et al. Intradiscal steroids: A prospective double-blind clinical trial. Spine. 1992; 17:172–175.
28). Nelemans PL, deBie RA, deVet HCW, Sturmans F. Injection therapy for subacute and chronic benign low back pain. Spine. 2001; 26:501–515.
crossref
29). Kozak JA, O’ Brien JP. Simultaneous combined anterior and posterior fusion. An independent analysis of a treatment for the disabled low-back pain patient. Spine. 1990; 15:322–328.
30). Slosar PJ, Reynolds JB, Schofferman J, Goldthwaite N, White AH, Keaney D.Patient satisfaction after cir -cumferential lumbar fusion. Spine. 2000; 25:722–726.
31). Albert TJ, Pinto M, Denis F. Management of symptomatic lumbar pseudarthrosis with anteroposterior fusion. A functional and radiographic outcome study. Spine. 2000; 25:123–129. ;discussion 130.

Table 1.
Correlations between age and response of marcaine
age Group A Group B Total
-30 3 3 6
31-35 2 3 5
36-40 3 3 6
41- 8 4 12

* Group A : Marcaine(+), Group B : Marcaine(-) (p>0.05)

Table 2.
Correlations between duration of symptom and response of marcaine
Duration of Sx Group A Group B Total
Below 2 years 4 7 11
2-5 years 3 3 6
Above 5 years 9 2 11

* Group A : Marcaine(+), Group B : Marcaine(-)(p<0.05)

Table 3.
Correlations between subjective pain and response of marcaine
10 point pain scale Group A Group B Total
7 4 4 8
8 4 4 8
9 5 3 8
10 3 2 5

* Group A : Marcaine(+), Group B : Marcaine(-) (p>0.05)

Table 4.
Correlations between No. of degenerative disc and response of marcaine
degenerative disc Group A Group B Total
1 segment 6 7 13
2 segments 5 3 8
3 segments 3 2 5
4 segments 2 1 3

* Group A : Marcaine(+), Group B : Marcaine(-)(p>0.05)

Table 5.
Correlations between HIZ and response of marcaine
Group A Group B Total
HIZ (+) 3 8 11
HIZ (-) 13 5 18

* Group A : Marcaine(+), Group B : Marcaine(-)* HIZ = High-intensity zone (p>0.05)

Table 6.
Outcomes of treatment results in Group A1
Preop. Last F/U
10-point pain scale 8.6± 0.97 1.8± 0.42%.
ODI 68± 16.92% 30± 9.97%

* ODI : Oswestry Disability Index (p<0.05)

Table 7.
Outcomes of treatment results in group B1
Initial Last F/U
10-point pain scale 8.3± 1.5800 4.9± 2.5300
ODI 59.4± 19.48% 29.4± 22.56%

* ODI : Oswestry Disability Index (p>0.05)

TOOLS
Similar articles