Abstract
Typhoid fever frequently manifests as gastrointestinal complications, such as ileitis or colitis, but appendicitis is quite rare. A 37-year-old man was admitted due to abdominal pain, fever and diarrhea. Two weeks before admission, he underwent an appendectomy. The blood culture upon admission revealed Salmonella Typhi. A polymerase chain reaction(PCR) was performed on the tissue of the vermiform appendix and the STY0312 gene of S. Typhi was detected. This is the first case of acute appendicitis complicated with typhoid fever proven by PCR in Korea.
References
1. Black PH, Kunz LJ, Swartz MN. Salmonellosis - a review of some unsusual aspects. N Engl J Med. 1960. 262:921–927.
2. Manganaro A, Impellizzeri P, Manganaro A, Cutrupi A, Formica I, Zuccarello B. Acute abdomen caused by Salmonella Typhi acute appendiciti S. Minerva Pediatr. 2006. 58:203–205.
3. Lau SK, Woo PC, Chan CY, Woo WL, Woo GK, Yuen KY. Typhoid fever associated with acute appendicitis caused by an H1-j strain of Salmonella enterica serotype Typhi. J Clin Microbiol. 2005. 43:1470–1472.
4. Grimes DA. Spontaneous perforation of the gallbladder from cholecystitis with acute appendicitis in pregnancy. A case report. J Reprod Med. 1996. 41:450–452.
5. Reller ME, Zaidi AK, Sultana S, Azeem S, Hanif B, Qureshi S, Hasan R, Bhutta Z, Akhter R, Goldmann DA. Controlled evaluation of Bactec Peds Plus/F and Bactec lytic/10 anaerobic/F media for isolation of Salmonella enterica serovars typhi and paratyphi A from blood. J Clin Microbiol. 2009. 47:245–246.
6. Nagarajan AG, Karnam G, Lahiri A, Allam US, Chakravortty D. Reliable means of diagnosis and serovar determination of blood-borne Salmonella strains: quick PCR amplification of unique genomic loci by novel primer sets. J Clin Microbiol. 2009. 47:2435–2441.
7. Likitnukul S, Wongsawat J, Nunthapisud P. Appendicitis-like syndrome owing to mesenteric adenitis caused by Salmonella Typhi. Ann Trop Paediatr. 2002. 22:97–99.
8. Meng GR. Acute mesenteric lymphadenitis due to Salmonella enteritidis mimicking appendicitis: case report. Mil Med. 1974. 139:277.
9. Martin HC, Goon HK. Salmonella ileocecal lymphadentitis masquerding as appenditis. J Pediatr Surg. 1986. 21:377–378.
10. Knight PJ, Vassy LE. Specific diseases mimicking appendicitis in childhood. Arch Surg. 1981. 116:744–746.
11. Bartoli F, Guerra A, Dolina M, Bianchetti MG. Salmonella enterica serovar Israel causing perforating appendicitis. Int J Infect Dis. 2010. 14:e538.
12. Kazlow PG, Freed J, Rosh JR, Reiner M, Dische R, Benkov K, LeLeiko NS. Salmonella typhimurium appendicitis. J Pediatr Gastroenterol Nutr. 1991. 13:101–103.
13. Deutsch A, Wasserman D, Ruchelli E, Johnson J, Broussard DL. An uncommon presentation of Salmonella. Pediatr Emerg Care. 1996. 12:285–287.
14. Scheidegger C, Frei R. Perforating appendicitis due to Salmonella hofit. Lancet. 1990. 335:59–60.