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Abstract
There are several clinical guidelines for the diagnosis and treatment of HIV/AIDS which are used extensively in other countries. However, the implementation of such guidelines is not assured due to the currently available situations for the diagnostic tests and antiretroviral drugs in Korea. Therefore, the Committee for Clinical Guidelines for the Diagnosis and Treatment of HIV/AIDS of The Korean Society for AIDS was founded in 2010 to develop an optimal guidelines which can be directly applied in Korea. This guideline aims to provide comprehensive information regarding the diagnosis and management of HIV/AIDS in Korea. The recommendations contain important information for physicians working with HIV/AIDS in actual clinical fields. The regular revision of the guideline will be done according to the change of the available situations for the diagnosis and treatment of HIV/AIDS.
Figures and Tables
Table 5
Initial Combination Regimen for Antiretroviral-Naïve Patients
aFatal hypersensitivity reaction could be happen by ABC, retrial is contraindicated when hypersensitivity reaction is suspicious.
bThe relationship between hypersensitivity reaction and HLA-B*5701 was proved in other ethnic groups.
cSpecial caution is required when ABC is used in patients with (a) cardiovascular risk factor(s).
dRitonavir-boosted PI.
eZDV and 3TC co-formulated drug is available.
fEither LPV/r 400mg/100mg bid or 800 mg/200 mg qd is acceptable.
gShould not be used during 1st trimester of pregnancy or in women with no effective and consistent contraception.
hIneffective in treating HIV-2 or HIV-1 group O infection.
iSevere hypersensitivity reaction is possible and special caution should be paid when used with ABC.
jExtreme caution should be paid when NPV is used in women with CD4+T cell > 250 cells/µL and men with CD4+ T cell > 400 cells/µL.
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