Epidemic by Salmonella I 4,[5],12:i:- and Characteristics of Isolates in Korea

Deog-Yong Lee; Esther Lee; Jung Eun Min; Seong Han Kim; Hee-Bok Oh; Mi-Sun Park

doi:10.3947/ic.2011.43.2.186

Journal List > Infect Chemother > v.43(2) > 1035072

Go to TopGo to Top Go to BottomGo to Bottom

TOOLS

Lee, Lee, Min, Kim, Oh, and Park: Epidemic by Salmonella I 4,[5],12:i:- and Characteristics of Isolates in Korea

Original Article

Infection & Chemotherapy

Infection & Chemotherapy 2011; 43(2): 186-190.

Published online: 30 April 2011

DOI: https://doi.org/10.3947/ic.2011.43.2.186

Epidemic by Salmonella I 4,[5],12:i:- and Characteristics of Isolates in Korea

Deog-Yong Lee, Esther Lee, Jung Eun Min, Seong Han Kim, Hee-Bok Oh, Mi-Sun Park

Division of Enteric Bacterial Infections, Center for Infectious Disease, National Institute of Health, KCDC, Seoul, Korea.

Correspondence to Mi-Sun Park Division of Enteric Bactrial Infections, Center for Infectious Diseases, KCDC, Osong Health Technology Administration Complex, 187 Osongsaemyoung 2(i)-gu, gangoe-myen, Cheongwon-gun, Chungcheogbuk-do 363-951, Korea. Tel: +82-43-719-8113, Fax: +82-43-719-8149, pmsun63@korea.kr

Received 27 July 2010 Revised 13 January 2011 Accepted 14 January 2011

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background

Salmonella I 4,[5],12:i:- was first reported as a new serovar by the Spanish National Reference Laboratory in 1997. Thereafter, several outbreaks caused by this serovar have been reported, indicating worldwide transmission.

Materials and Methods

Stool samples and patient data were collected from diarrhea cases in an outbreak at Daegu city in 2008. Salmonella isolates were characterized by phage typing, antibiotic resistance profile and flagella gene deletion. Deposited isolates in the EnterNet-Korea, acute diarrheal surveillance system, were also screened for this serovar.

Results

Isolates from diarrhea patients in the Daegu outbreak (2008) were identified as Salmonella I 4,[5],12:i:-. Screening the deposited isolates in the EnteroNet-Korea revealed that an unidentifed isolate in 2001 was the Salmonella I 4,[5], 12:i:-.

Conclusions

Salmonella I 4,[5],12:i:-. was the causative pathogen of the 2008 foodborne outbreak of salmonellosis in Daegu City. Retrospective screening revealed that Salmonella I 4,[5],12:i:- was present in Korea as early as 2001.

Keywords: Salmonella I 4,[5],12:i:-, Antibiotic resistance, Phage type

Figures and Tables

Table 1

Characteristics of Salmonella I 4,[5],12:i:- Isolated from Human Diarrheal Feces in Korea

^aR type: resistance type

^bAntibiotic resistance against ampicillin, ampicillin/sulbactam, nalidixic acid, tetracycline, ticarcillin

^cAntibiotic resistance against ampicillin, nalidixic acid, tetracycline, ticarcillin

^dAntibiotic resistance against tetracycline

^eAntibiotic resistance against ampicillin, chloramphenicol, ticarcillin, streptomycin

^fAntibiotic resistance against ampicillin, tetracycline, ticarcillin, streptomycin

^gAntibiotic resistance against ampicillin

References

1. Grimont PAD, Weill F. WHO Collaborating Centre for Reference and Research on Salmonella. Antigenic formulae of the Salmonella serovars. 2007. 9th ed. Paris: Institut Pasteur.

2. McQuiston JR, Fields PI, Tauxe RV, Logsdon JM Jr. Do Salmonella carry spare tyres? Trends Microbiol. 2008. 16:142–148.

3. McQuiston JR, Herrera-Leon S, Wertheim BC, Doyle J, Fields PI, Tauxe RV, Logsdon JM Jr. Molecular phylogeny of the salmonellae: relationships among Salmonella species and subspecies determined from four housekeeping genes and evidence of lateral gene transfer events. J Bacteriol. 2008. 190:7060–7067.

4. Agasan A, Kornblum J, Williams G, Pratt CC, Fleckenstein P, Wong M, Ramon A. Profile of Salmonella enterica subsp. enterica (subspecies I) serotype 4,5,12:i:- strains causing food-borne infections in New York City. J Clin Microbiol. 2002. 40:1924–1929.

5. Echeita MA, Herrera S, Usera MA. Atypical, fljB-negative Salmonella enterica subsp. enterica strain of serovar 4,5,12:i:- appears to be a monophasic variant of serovar Typhimurium. J Clin Microbiol. 2001. 39:2981–2983.

6. Echeita MA, Aladueña A, Cruchaga S, Usera MA. Emergence and spread of an atypical Salmonella enterica subsp. enterica serotype 4,5,12:i:- strain in Spain. J Clin Microbiol. 1999. 37:3425.

7. de la Torre E, Zapata D, Tello M, Mejia W, Frias N, Garcia Pena FJ, Mateu EM, Torre E. Several Salmonella enterica subsp. enterica serotype 4,5,12:i:- phage types isolated from swine samples originate from serotype typhimurium DT U302. J Clin Microbiol. 2003. 41:2395–2400.

8. Tavechio AT, Ghilardi AC, Fernandes SA. "Multiplex PCR" identification of the atypical and monophasic Salmonella enterica subsp. enterica serotype 1,4,[5],12:i:- in Sao Paulo State, Brazil: frequency and antibiotic resistance patterns. Rev Inst Med Trop Sao Paulo. 2004. 46:115–117.

9. Amavisit P, Boonyawiwat W, Bangtrakulnont A. Characterization of Salmonella enterica serovar Typhimurium and monophasic Salmonella serovar 1,4,[5],12:i:- isolates in Thailand. J Clin Microbiol. 2005. 43:2736–2740.

10. Guerra B, Laconcha I, Soto SM, González-Hevia MA, Mendoza MC. Molecular characterisation of emergent multiresistant Salmonella enterica serotype [4,5,12:i:-] organisms causing human salmonellosis. FEMS Microbiol Lett. 2000. 190:341–347.

11. Pornruangwong S, Sriyapai T, Pulsrikarn C, Sawanpanyalert P, Boonmar S, Bangtrakulnonth A. The epidemiological relationship between Salmonella enterica serovar typhimurium and Salmonella enterica serovar 4,[5],12:i:- isolates from humans and swine in Thailand. Southeast Asian J Trop Med Public Health. 2008. 39:288–296.

12. Mossong J, Marques P, Ragimbeau C, Huberty-Krau P, Losch S, Meyer G, Moris G, Strottner C, Rabsch W, Schneider F. Outbreaks of monophasic Salmonella enterica serovar 4,[5],12:i:- in Luxembourg, 2006. Euro Surveill. 2007. 12:E11–E12.

13. Investigation of Outbreak of Human Infections caused by Salmonella I 4,[5],12;i;-. Centers of Diseases Control and Prevention (CDC). Accessed 25 July 2010. Available at: http://www.cdc.gov/salmonella/4512eyeminus.html.

14. Lee DY. (Standard Operationg Procedure: KCDC-Sal-SE SOP 003). Serotyping of Salmonella spp. 2009. Seoul: KCDC.

15. Kim SH, Kim S, Lee SW, Kang YH, Lee BK. Rapid serological identification for monophasic Salmonella serovars with a hin gene: specific polymerase chain reaction. J Bacteriol Virol. 2005. 35:291–297.

16. Clinical and Laboratory Standards Institute. Document M100-S20. Performance standards for antimicrobial susceptibility testing; twentieth informational supplement. 2010. Wayne, PA: CLSI.

17. Soyer Y, Moreno Switt A, Davis MA, Maurer J, McDonough PL, Schoonmaker-Bopp DJ, Dumas NB, Root T, Warnick LD, Grohn YT, Wiedmann M. Salmonella enterica serotype 4,5,12:i:-, an emerging Salmonella serotype that represents multiple distinct clones. J Clin Microbiol. 2009. 47:3546–3556.

18. Zamperini K, Soni V, Waltman D, Sanchez S, Theriault EC, Bray J, Maurer JJ. Molecular characterization reveals Salmonella enterica serovar 4,[5],12:i:- from poultry is a variant Typhimurium serovar. Avian Dis. 2007. 51:958–964.

19. Centers of Diseases Control and Prevention (CDC). Salmonella surveillance: annual summary, 2006. 2008. Atlanta, Georgia: US Department of Health and Human Services, CDC.

20. Hopkins KL, Kirchner M, Guerra B, Granier SA, Lucarelli C, Porrero MC, Jakubczak A, Threlfall EJ, Mevius DJ. Multiresistant Salmonella enterica serovar 4,[5],12:i:- in Europe: a new pandemic strain? Euro Surveill. 2010. 15:19580.

21. Rabsch W, Andrews HL, Kingsley RA, Prager R, Tschäpe H, Adams LG, Bäumler AJ. serotype Typhimurium and its host-adapted variants. Infect Immun. 2002. 70:2249–2255.

TOOLS

Similar articles