Journal List > Infect Chemother > v.42(2) > 1035067

Kim, Kim, Uh, and Chun: Detection Rate of Rapid Antigen Test for Pandemic Influenza A (H1N1 2009)

Abstract

There are few datas on the diagnostic accuracy of rapid antigen test for pandemic influenza A (H1N1). We evaluated the performance of rapid antigen test for the diagnosis of pandemic influenza A (H1N1). During the period from 21 August 2009 to 20 September 2009, 451 patients with influenza-like symptom underwent the rapid antigen test (SD Influenza Antigen, Standard Diagnostics, Yongin, Korea) and real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) at the same time. Rapid antigen test results were positive for 65 of 90 patients with the positive results for pandemic influenza A (H1N1) on rRT-PCR assay. The sensitivity of the rapid antigen test was 72.2% (95% CI, 61.8-81.1) and the specificity was 100% (95% CI, 99.0-100). The positive predictive value was 100% (95% CI, 94.5-100) and negative predictive value was 93.5% (95% CI, 90.6-95.8).

Figures and Tables

Table 1
Performance of the Rrpid Influenza Aantigen Test for Diagnosis of Pandemic Influenza A (H1N1) according to Age
ic-42-95-i001

RIDT, rapid influenza diagnostic test; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; N/A, not applicable

Table 2
Performance of the Rapid Influenza Antigen test for Diagnosis of Pandemic Influenza A (H1N1) according to Symptom Interval
ic-42-95-i002

RIDT, rapid influenza diagnostic test; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; N/A, not applicable

Table 3
The Positivity of Rapid Antigen Test According to the Cycle Threshold (Ct) Value of Real-time RT-PCR
ic-42-95-i003

RIDT, rapid influenza diagnostic test

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