Journal List > Infect Chemother > v.42(6) > 1035054

Kim, Kim, Cheon, Suh, Lim, Heo, Sohn, Ko, and Bae: A Case of Duodenal Ulcer Due to Coinfection with Strongyloides stericoralis and Cytomegalovirus

Abstract

Gastrointestinal strongyloidiasis and Cytomegalovirus infection mostly occur in patients receiving cancer chemotherapy, undergoing immunosuppressive therapy after organ transplantation, and suffering from acquired immune deficiency syndrome. A 56-year-old man was admitted to the hospital because of abdominal pain and constipation. He had a 10-year history of chronic obstructive pulmonary disease and has been treated intermittently with systemic steroid. The gastroduodenoscopic examination showed a single ulcer on the duodenal bulb and microscopic finding of the biopsy specimens from the ulcer revealed Strongyloides stercoralis and cytomegalovirus immunohistochemical stain positive intranuclear inclusion body on the mucosal surface. The patient was successfully treated with albendazole and ganciclovir.

Figures and Tables

Figure 1
Microscopic appearance of Strongyloides stercoralis from duodenal biopsy specimen. A filariform larva (arrow) is seen in the lumen of an intestinal gland (H&E stain, ×200).
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Figure 2
Microscopic appearance of an intranuclear inclusion body from duodenal biopsy specimen. Several glandular epithelial cells (arrow) are enlarged and protrude into the glandular lumen. The nuclei of the cells contain large amphophilic viral inclusions (H&E stain, ×200).
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